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Article
Open AccessMultitissue H3K27ac profiling of GTEx samples links epigenomic variation to disease
Genetic variants associated with complex traits are primarily noncoding, and their effects on gene-regulatory activity remain largely uncharacterized. To address this, we profile epigenomic variation of histon...
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Prophylactic Versus Selective Central Neck Dissection in Pediatric Papillary Thyroid Cancer
The first case of thyroid carcinoma in a child was described in 1902. Following this, Crile published the first case series of pediatric thyroid cancer in 1959, whereby he characterized pediatric thyroid cance...
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Article
Open AccessCould the significantly increased risk of rheumatoid arthritis reported in Italian male steel workers be explained by occupational exposure to cadmium?
Multiple chronic disease risks have been identified in Italian furnace workers. A range of potential toxins have been identified in foundry dust. We suggest that the heavy metal cadmium (Cd) plays an important...
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Open AccessCharacteristics of contralateral carcinomas in patients with differentiated thyroid cancer larger than 1 cm
Traditionally, total thyroidectomy has been advocated for patients with tumors larger than 1 cm. However, according to the ATA and NCCN guidelines (2015, USA), patients with tumors up to 4 cm are now eligible ...