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2,428 Result(s)
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Article
Open AccessIdentifying symptom etiologies using syntactic patterns and large language models
Differential diagnosis is a crucial aspect of medical practice, as it guides clinicians to accurate diagnoses and effective treatment plans. Traditional resources, such as medical books and services like UpToD...
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Open AccessDifferent humidity environments do not affect the subsequent exercise ability of college football players after aerobic high-intensity interval training
Previous studies have explored the effect of differing heat and relative humidity (RH) environments on the performance of multiple anaerobic high-intensity interval training (HIIT). Still, its impact on physio...
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Open AccessSetting the morphologic quality limits enabling accurate classification of charred archaeological grape seeds
This study investigates the morphological changes in grape pips resulting from various charring conditions. Employing high-resolution scanning combined with morphometric measurements for morphological analysis...
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Open AccessWhite-light activatable organic NIR-II luminescence nanomaterials for imaging-guided surgery
While second near-infrared (NIR-II) fluorescence imaging is a promising tool for real-time surveillance of surgical operations, the previously reported organic NIR-II luminescent materials for in vivo imaging ...
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Phage anti-CRISPR control by an RNA- and DNA-binding helix–turn–helix protein
In all organisms, regulation of gene expression must be adjusted to meet cellular requirements and frequently involves helix–turn–helix (HTH) domain proteins1. For instance, in the arms race between bacteria and ...
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Open AccessEgg multivesicular bodies elicit an LC3-associated phagocytosis-like pathway to degrade paternal mitochondria after fertilization
Mitochondria are maternally inherited, but the mechanisms underlying paternal mitochondrial elimination after fertilization are far less clear. Using Drosophila, we show that special egg-derived multivesicular bo...
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Open AccessRadially distributed charging time constants at an electrode-solution interface
An electrochemically homogeneous electrode-solution interface should be understood as spatially invariant in both terms of intrinsic reactivity for the electrode side and electrical resistance mainly for the s...
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Open AccessLate Holocene echinoderm assemblages can serve as paleoenvironmental tracers in an Antarctic fjord
High Latitude fjords can serve as sediment trap, bearing different type of proxies, from geochemical to micropaleontological ones, making them exceptional tools for paleoenvironmental reconstruction. However, ...
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Open AccessSpike deep mutational scanning helps predict success of SARS-CoV-2 clades
SARS-CoV-2 variants acquire mutations in the spike protein that promote immune evasion1 and affect other properties that contribute to viral fitness, such as ACE2 receptor binding and cell entry2,3. Knowledge of ...
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Open AccessAnalysis of culture and RNA isolation methods for precision-cut liver slices from cirrhotic rats
Precision-cut liver slices (PCLS) are increasingly used as a model to investigate anti-fibrotic therapies. However, many studies use PCLS from healthy animals treated with pro-fibrotic stimuli in culture, whic...
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Open AccessHuman SARS-CoV-2 challenge uncovers local and systemic response dynamics
The COVID-19 pandemic is an ongoing global health threat, yet our understanding of the dynamics of early cellular responses to this disease remains limited1. Here in our SARS-CoV-2 human challenge study, we used ...
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Open AccessThe mechanism for directional hearing in fish
Locating sound sources such as prey or predators is critical for survival in many vertebrates. Terrestrial vertebrates locate sources by measuring the time delay and intensity difference of sound pressure at e...
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Open AccessAuthor Correction: Capturing electron-driven chiral dynamics in UV-excited molecules
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Detection of Ochratoxin A Mycotoxin with Graphene Nanosheets Functionalized with Selective Peptides Using Molecular Dynamics
Ochratoxin A (OTA) is a mycotoxin commonly found in improperly stored grains, posing significant risks to food safety. Accurate detection of this mycotoxin in food matrices is crucial for ensuring consumer pro...
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Open AccessMineral accumulation, relative water content and gas exchange are the main physiological regulating mechanisms to cope with salt stress in barley
Salinity has become a major environmental concern for agricultural lands, leading to decreased crop yields. Hence, plant biology experts aim to genetically improve barley’s adaptation to salinity stress by dee...
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Open AccessSpontaneous rates exhibit high intra-individual stability across movements involving different biomechanical systems and cognitive demands
Spontaneous rhythmic movements are part of everyday life, e.g., in walking, clap** or music making. Humans perform such spontaneous motor actions at different rates that reflect specific biomechanical constr...
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Open AccessObservation of heat pum** effect by radiative shuttling
Heat shuttling phenomenon is characterized by the presence of a non-zero heat flow between two bodies without net thermal bias on average. It was initially predicted in the context of nonlinear heat conduction...
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Open AccessBorg extrachromosomal elements of methane-oxidizing archaea have conserved and expressed genetic repertoires
Borgs are huge extrachromosomal elements (ECE) of anaerobic methane-consuming “Candidatus Methanoperedens” archaea. Here, we used nanopore sequencing to validate published complete genomes curated from short read...
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Open AccessIdentifying significant structural factors associated with knee pain severity in patients with osteoarthritis using machine learning
Our main objective was to use machine learning methods to identify significant structural factors associated with pain severity in knee osteoarthritis patients. Additionally, we assessed the potential of vario...
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Open AccessROCOv2: Radiology Objects in COntext Version 2, an Updated Multimodal Image Dataset
Automated medical image analysis systems often require large amounts of training data with high quality labels, which are difficult and time consuming to generate. This paper introduces Radiology Object in COn...