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  1. Article

    Open Access

    New Abundant Microbial Groups in Aquatic Hypersaline Environments

    We describe the microbiota of two hypersaline saltern ponds, one of intermediate salinity (19%) and a NaCl saturated crystallizer pond (37%) using pyrosequencing. The analyses of these metagenomes (nearly 784 ...

    Rohit Ghai, Lejla Pašić, Ana Beatriz Fernández in Scientific Reports (2011)

  2. No Access

    Article

    Explaining microbial population genomics through phage predation

    Not all isolates of a species contain the same set of genes. In this Opinion article, Rodriguez-Valera and colleagues propose the constant-diversity model to account for these differences. In this model, preda...

    Francisco Rodriguez-Valera, Ana-Belen Martin-Cuadrado in Nature Reviews Microbiology (2009)

  3. Article

    Erratum: Functional metagenomic profiling of nine biomes

    Nature 452, 629–632 (2008) In this Letter, functional diversity and evenness were calculated using log10, but it has been drawn to our attention that the calculations should have been made with natural logs (T...

    Elizabeth A. Dinsdale, Robert A. Edwards, Dana Hall, Florent Angly, Mya Breitbart in Nature (2008)

  4. No Access

    Article

    Functional metagenomic profiling of nine biomes

    Nearly 15 million sequences were used in a comparative metagenomic study of 45 microbiomes and 42 viriomes (the latter dominated by bacteriophage) from nine distinct types of ecosystem, varying from coral reef...

    Elizabeth A. Dinsdale, Robert A. Edwards, Dana Hall, Florent Angly, Mya Breitbart in Nature (2008)

  5. No Access

    Article

    Biodiversity and biogeography of phages in modern stromatolites and thrombolites

    Stromatolites are living, layered structures formed in shallow waters by a combination of microbial biofilms — usually of blue-green algae — and granular deposits. They are rare today but for about 2 billion y...

    Christelle Desnues, Beltran Rodriguez-Brito, Steve Rayhawk, Scott Kelley in Nature (2008)

  6. Article

    Open Access

    Using pyrosequencing to shed light on deep mine microbial ecology

    Contrasting biological, chemical and hydrogeological analyses highlights the fundamental processes that shape different environments. Generating and interpreting the biological sequence data was a costly and t...

    Robert A Edwards, Beltran Rodriguez-Brito, Linda Wegley, Matthew Haynes in BMC Genomics (2006)

  7. Article

    Open Access

    An application of statistics to comparative metagenomics

    Metagenomics, sequence analyses of genomic DNA isolated directly from the environments, can be used to identify organisms and model community dynamics of a particular ecosystem. Metagenomics also has the poten...

    Beltran Rodriguez-Brito, Forest Rohwer, Robert A Edwards in BMC Bioinformatics (2006)

  8. Article

    Open Access

    PHACCS, an online tool for estimating the structure and diversity of uncultured viral communities using metagenomic information

    Phages, viruses that infect prokaryotes, are the most abundant microbes in the world. A major limitation to studying these viruses is the difficulty of cultivating the appropriate prokaryotic hosts. One way ar...

    Florent Angly, Beltran Rodriguez-Brito, David Bangor, Pat McNairnie in BMC Bioinformatics (2005)