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Open AccessNew Abundant Microbial Groups in Aquatic Hypersaline Environments
We describe the microbiota of two hypersaline saltern ponds, one of intermediate salinity (19%) and a NaCl saturated crystallizer pond (37%) using pyrosequencing. The analyses of these metagenomes (nearly 784 ...
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Article
Explaining microbial population genomics through phage predation
Not all isolates of a species contain the same set of genes. In this Opinion article, Rodriguez-Valera and colleagues propose the constant-diversity model to account for these differences. In this model, preda...
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Article
Erratum: Functional metagenomic profiling of nine biomes
Nature 452, 629–632 (2008) In this Letter, functional diversity and evenness were calculated using log10, but it has been drawn to our attention that the calculations should have been made with natural logs (T...
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Functional metagenomic profiling of nine biomes
Nearly 15 million sequences were used in a comparative metagenomic study of 45 microbiomes and 42 viriomes (the latter dominated by bacteriophage) from nine distinct types of ecosystem, varying from coral reef...
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Article
Biodiversity and biogeography of phages in modern stromatolites and thrombolites
Stromatolites are living, layered structures formed in shallow waters by a combination of microbial biofilms — usually of blue-green algae — and granular deposits. They are rare today but for about 2 billion y...
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Open AccessUsing pyrosequencing to shed light on deep mine microbial ecology
Contrasting biological, chemical and hydrogeological analyses highlights the fundamental processes that shape different environments. Generating and interpreting the biological sequence data was a costly and t...
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Open AccessAn application of statistics to comparative metagenomics
Metagenomics, sequence analyses of genomic DNA isolated directly from the environments, can be used to identify organisms and model community dynamics of a particular ecosystem. Metagenomics also has the poten...
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Open AccessPHACCS, an online tool for estimating the structure and diversity of uncultured viral communities using metagenomic information
Phages, viruses that infect prokaryotes, are the most abundant microbes in the world. A major limitation to studying these viruses is the difficulty of cultivating the appropriate prokaryotic hosts. One way ar...