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  1. No Access

    Article

    Intracellular immune sensing promotes inflammation via gasdermin D–driven release of a lectin alarmin

    Inflammatory caspase sensing of cytosolic lipopolysaccharide (LPS) triggers pyroptosis and the concurrent release of damage-associated molecular patterns (DAMPs). Collectively, DAMPs are key determinants that ...

    Ashley J. Russo, Swathy O. Vasudevan, Santiago P. Méndez-Huergo… in Nature Immunology (2021)

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    Reference Work Entry In depth

    MicroRNA-Regulated Immune Cell Function in Obese Adipose Tissue

    Low-grade tissue inflammation is a key driver for the development of obesity-induced insulin resistance with a remarkable accumulation of various immune cells in adipose tissues. The proinflammatory activation...

    Beiyan Zhou, Wei Ying, Chuan Li… in Handbook of Nutrition, Diet, and Epigeneti… (2019)

  3. No Access

    Living Reference Work Entry In depth

    MicroRNA-Regulated Immune Cell Function in Obese Adipose Tissue

    Low-grade tissue inflammation is a key driver for the development of obesity-induced insulin resistance with a remarkable accumulation of various immune cells in adipose tissues. The proinflammatory activation...

    Beiyan Zhou, Wei Ying, Chuan Li… in Handbook of Nutrition, Diet, and Epigeneti…

  4. Article

    Open Access

    miR-150 regulates obesity-associated insulin resistance by controlling B cell functions

    Adipose tissue resident B cells account for more than 20% of stromal cells within visceral adipose tissues; however, their functions in the adipose tissue niche are poorly elucidated. Here we report that miR-1...

    Wei Ying, Alexander Tseng, Richard Cheng-An Chang, Haiqing Wang… in Scientific Reports (2016)

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    Article

    The many faces of interferon tau

    Interferon tau (IFNT) was discovered as the pregnancy recognition signal in ruminants, but is now known to have a plethora of physiological functions in the mammalian uterus. The mammalian uterus includes, fro...

    Fuller W. Bazer, Wei Ying, **aoqiu Wang, Kathrin A. Dunlap, Beiyan Zhou… in Amino Acids (2015)

  6. No Access

    Chapter

    NR4A Orphan Receptors as Drug Targets

    The orphan receptor NR4Al (Nur77, TR3, NGFI-B) is overexpressed in many different cancer cell lines and tumors, and, in leukemia cells, NR4Al is also more highly expressed than in B- or T-cell. In contrast, we...

    Stephen Safe, Syng-Ook Lee, Cong Meng… in Targeted Therapy of Acute Myeloid Leukemia (2015)

  7. Article

    Erratum: Micromanagement of the immune system by microRNAs

    Nature Reviews Immunology 8, 120–130 (2008) The authors for reference 97 were published incorrectly. It should have read: Wu, H. et al.

    Harvey F. Lodish, Beiyan Zhou, Gwen Liu, Chang-Zheng Chen in Nature Reviews Immunology (2008)

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  8. No Access

    Article

    Micromanagement of the immune system by microRNAs

  9. MicroRNA (miRNA) genes encode long primary RNA transcripts that are processed into a precursor miRNA (pre-miRNA) that is ∼60 nucleotides in length. The pre-miR...

    10. Harvey F. Lodish, Beiyan Zhou, Gwen Liu, Chang-Zheng Chen in Nature Reviews Immunology (2008)

  10. No Access

    Protocol

    Analysis of Placental Regulation of Hematopoiesis

    Placental hormones contribute to changes in maternal physiology, especially to changes in the blood system. Methods are described to express a placental hormone from a cloned cDNA by transfection into a mammal...

    Beiyan Zhou, Daniel I. H. Linzer in Placenta and Trophoblast (2006)