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Article
17β-Estradiol-induced antidepressant-like effect in the Forced Swim Test is absent in estrogen receptor-β knockout (BERKO) mice
The decrease in levels of estrogens (ER) that occurs in menopause has been correlated with depressive disorders, probably due to ER direct and/or indirect effects in the brain, where these hormones act through...
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Article
Sensitization of Psychomotor Stimulation and Conditioned Reward in Mice: Differential Modulation by Contextual Learning
Incentive motivation theory ascribes a critical role to reward-associated stimuli in the generation and maintenance of goal-directed behavior. Repeated psychomotor stimulant treatment, in addition to producing...
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Article
Increased vulnerability to self-administer cocaine in mice prenatally exposed to cocaine
Abstract
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Article
Reinstatement of cocaine seeking in 129X1/SvJ mice: effects of cocaine priming, cocaine cues and food deprivation
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Article
Cocaine self-administration in dopamine-transporter knockout mice
The plasma membrane dopamine transporter (DAT) is responsible for clearing dopamine from the synapse. Cocaine blockade of DAT leads to increased extracellular dopamine, an effect widely considered to be the pr...
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Article
Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor
There is increasing evidence that genetic factors can influence individual differences in vulnerability to drugs of abuse1,2. Serotonin (5-hydroxytryptamine, 5-HT), acting through many receptors can modulate the ...