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  1. Article

    Open Access

    Pre-clinical validation of a pan-cancer CAR-T cell immunotherapy targeting nfP2X7

    Chimeric antigen receptor (CAR)-T cell immunotherapy is a novel treatment that genetically modifies the patients’ own T cells to target and kill malignant cells. However, identification of tumour-specific anti...

    Veronika Bandara, Jade Foeng, Batjargal Gundsambuu, Todd S. Norton in Nature Communications (2023)

  2. Article

    Open Access

    Parallel recovery of chromatin accessibility and gene expression dynamics from frozen human regulatory T cells

    Epigenetic features such as DNA accessibility dictate transcriptional regulation in a cell type- and cell state- specific manner, and map** this in health vs. disease in clinically relevant material is openi...

    Ying Y. Wong, Jessica E. Harbison, Christopher M. Hope in Scientific Reports (2023)

  3. No Access

    Protocol

    Studying Permeability in a Commonly Used Epithelial Cell Line: T84 Intestinal Epithelial Cells

    The integrity, or barrier function, of the intestinal epithelium is of paramount importance in ­maintaining good health. This is largely imparted by a single layer of epithelial cells linked by the transmembra...

    Rino P. Donato, Adaweyah El-Merhibi, Batjargal Gundsambuu in Permeability Barrier (2011)