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Article
De novo emerged stemness signatures in epithelial monolayers developed from extirpated palleal buds
In botryllid ascidians, astogeny is executed through blastogenesis, a weekly, highly synchronized phenomenon of growth and death cycles, each constitutes four major developmental stages (A–D), operating simult...
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Article
Further portrayal of epithelial monolayers emergent de novo from extirpated ascidians palleal buds
Astogeny in botryllid ascidians is executed by highly synchronized, repeated development and death cycles operating simultaneously on three coexisting asexually derived generations: zooids, primary buds, and s...
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Book
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Chapter
Stem Cells: Autonomy Interactors that Emerge as Causal Agents and Legitimate Units of Selection
Can stem cells be defined as legitimate units of selection (UOS)? Here I review traits of hallmark stem cells (many of which are manifested in marine organisms), which collectively reveal that some types of st...
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Chapter
Stem Cells in Aquatic Invertebrates: Common Premises and Emerging Unique Themes
The remarkable ability to generate an embryo from a single fertilized oocyte and to regenerate tissues that are injured or going through natural physiological turnover, is the direct result of stem cells, natu...
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Chapter
Stem Cells, Chimerism and Tolerance: Lessons from Mammals and Ascidians
Chimerism is the presence of cells derived from more than one individual in a given individual. This phenomenon has been detected in a wide variety of multicellular organisms, including vertebrates. In mammals...
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Article
Further steps in the initiation of cell cultures from embryos and adult sponge colonies
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Article
Initiation of epithelial cell cultures from palleal buds of Botryllus schlosseri, a colonial tunicate
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Article
In vitro culture of blood cells from the colonial protochordateBotryllus schlosseri
Primary cultures of circulatory blood cells from the colonial tunicateBotryllus schlosseri were cultivated in 96-well plates for up to 3 mo. in a medium based on Dulbecco’s modified Eagle’s medium, supplemented w...