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Article
Long-term changes in population genetic features of a rapidly expanding marine invader: implication for invasion success
Large blooms of Rhopilema nomadica, a highly venomous rhizostamatid scyphozoan species introduced to the Mediterranean through the Suez Canal, have become ubiquitous in the summer and winter months along the Isra...
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Article
The Apex Set-Up for the Major Transitions in Individuality
Morphological and functional hierarchies occurring in contemporary biological entities are amalgamated via a small number of progressive key-steps termed as Major Transition in Evolution (MTE) that encompass s...
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Article
Long-term population genetic structure of an invasive urochordate: the ascidian Botryllus schlosseri
The accelerated pace of marine biological invasions raises questions pertaining to genetic traits and dynamics underlying the successful establishment of invasive species. Current research stresses the importa...
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Article
De novo emerged stemness signatures in epithelial monolayers developed from extirpated palleal buds
In botryllid ascidians, astogeny is executed through blastogenesis, a weekly, highly synchronized phenomenon of growth and death cycles, each constitutes four major developmental stages (A–D), operating simult...
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Article
Further portrayal of epithelial monolayers emergent de novo from extirpated ascidians palleal buds
Astogeny in botryllid ascidians is executed by highly synchronized, repeated development and death cycles operating simultaneously on three coexisting asexually derived generations: zooids, primary buds, and s...
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Book
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Chapter
Stem Cells: Autonomy Interactors that Emerge as Causal Agents and Legitimate Units of Selection
Can stem cells be defined as legitimate units of selection (UOS)? Here I review traits of hallmark stem cells (many of which are manifested in marine organisms), which collectively reveal that some types of st...
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Chapter
Stem Cells in Aquatic Invertebrates: Common Premises and Emerging Unique Themes
The remarkable ability to generate an embryo from a single fertilized oocyte and to regenerate tissues that are injured or going through natural physiological turnover, is the direct result of stem cells, natu...
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Chapter
Stem Cells, Chimerism and Tolerance: Lessons from Mammals and Ascidians
Chimerism is the presence of cells derived from more than one individual in a given individual. This phenomenon has been detected in a wide variety of multicellular organisms, including vertebrates. In mammals...
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Article
Open AccessCell signaling and transcription factor genes expressed during whole body regeneration in a colonial chordate
The restoration of adults from fragments of blood vessels in botryllid ascidians (termed whole body regeneration [WBR]) represents an inimitable event in the chordates, which is poorly understood on the mechan...
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Article
Further steps in the initiation of cell cultures from embryos and adult sponge colonies
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Article
Initiation of epithelial cell cultures from palleal buds of Botryllus schlosseri, a colonial tunicate
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Article
In vitro culture of blood cells from the colonial protochordateBotryllus schlosseri
Primary cultures of circulatory blood cells from the colonial tunicateBotryllus schlosseri were cultivated in 96-well plates for up to 3 mo. in a medium based on Dulbecco’s modified Eagle’s medium, supplemented w...