95 Result(s)
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Baohong **
Life Sciences
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Article
Open AccessSingle-cell RNA sequencing opens a new era for cotton genomic research and gene functional analysis
Single-cell RNA sequencing (scRNA-seq) is one of the most advanced sequencing technologies for studying transcriptome landscape at the single-cell revolution. It provides numerous advantages over traditional R...
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Calcium-sensing receptor and NF-κB pathways in TN breast cancer contribute to cancer-induced cardiomyocyte damage via activating neutrophil extracellular traps formation
Cardiovascular disorders are commonly prevalent in cancer patients, yet the mechanistic link between them remains poorly understood. Because neutrophil extracellular traps (NETs) have implications not just in ...
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Open AccessDynamic physiological and transcriptomic changes reveal memory effects of salt stress in maize
Pre-exposing plants to abiotic stresses can induce stress memory, which is crucial for adapting to subsequent stress exposure. Although numerous genes involved in salt stress response have been identified, the...
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Open AccessVirulence, antimicrobial resistance, and molecular characteristics of carbapenem-resistant Klebsiella pneumoniae in a hospital in Shijiazhuang City from China
Carbapenem-resistant Klebsiella pneumoniae (CRKP), as one of the most common drug-resistant bacteria threatening human health, is hyper-resistant to multiple antimicrobial drugs and carbapenems, which can be deal...
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Open AccessHuman Amniotic Mesenchymal Stem Cells Alleviate aGVHD after allo-HSCT by Regulating Interactions between Gut Microbiota and Intestinal Immunity
Acute graft-versus-host disease (aGVHD) after allogeneic hematopoietic stem cell transplantation poses one of the most vexing challenges. Gut microbiota dysbiosis can proceed aGVHD and mesenchymal stem cells (...
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Editing of TOM1 gene in tobacco using CRISPR/Cas9 confers resistance to Tobacco mosaic virus
Genome editing technology has become one of the excellent tools for precise plant breeding to develop novel plant germplasm. The Tobacco mosaic virus (TMV) is the most prominent pathogen that infects several Sola...
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A review on CRISPR/Cas: a versatile tool for cancer screening, diagnosis, and clinic treatment
Cancer is one of the leading causes of death worldwide and it has the trend of increase incidence. However, in the past decades, as quickly developed new technologies and modified old techniques for cancer scr...
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The resilient cotton plant: uncovering the effects of stresses on secondary metabolomics and its underlying molecular mechanisms
Cotton is an important fiber crop cultivated around the world under diverse climate conditions and generates billions of dollars in annual revenue globally. Biotic and abiotic stresses have caused reduction in...
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Open AccessscRNASequest: an ecosystem of scRNA-seq analysis, visualization, and publishing
Single-cell RNA sequencing is a state-of-the-art technology to understand gene expression in complex tissues. With the growing amount of data being generated, the standardization and automation of data analysi...
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Insights to Gossypium defense response against Verticillium dahliae: the Cotton Cancer
The soil-borne pathogen Verticillium dahliae, also referred as “The Cotton Cancer,” is responsible for causing Verticillium wilt in cotton crops, a destructive disease with a global impact. To infect cotton plant...
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Associations Between the Lead Level in Maternal Blood and Umbilical Cord Blood and Congenital Heart Diseases in Offspring
The incidence of congenital heart diseases (CHDs) shows an increasing trend and results in large health burdens in China. However, there have been inconsistent results of the relationship between lead (Pb) lev...
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RefFinder: a web-based tool for comprehensively analyzing and identifying reference genes
Although many genes may serve as reference genes, they may cause different expression patterns by selecting different reference genes because no single gene is expressed consistently in all tested tissues of a...
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Microbial assemblages of Schisandraceae plants and the correlations between endophytic species and the accumulation of secondary metabolites
Schisandraceae are medicinal plants with significant medicinal and economic value. However, little is known about the microbiota assembly of Schisandraceae plants and the relationship between endophytic specie...
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The landscape of genome sequencing and assembling in plants
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Open AccessCorrection: Cholecystectomy promotes colon carcinogenesis by activating the Wnt signaling pathway by increasing the deoxycholic acid level
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KMT2C deficiency promotes small cell lung cancer metastasis through DNMT3A-mediated epigenetic reprogramming
Small cell lung cancer (SCLC) is notorious for its early and frequent metastases, which contribute to it as a recalcitrant malignancy. To understand the molecular mechanisms underlying SCLC metastasis, we gene...
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Open AccessCholecystectomy promotes colon carcinogenesis by activating the Wnt signaling pathway by increasing the deoxycholic acid level
Cholecystectomy (XGB) is widely recognized as a risk factor for colon cancer (CC). Continuous exposure of the colonic epithelium to deoxycholic acid (DCA) post-XGB may exert cytotoxic effects and be involved i...
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Open AccessBroad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) continue to wreak havoc across the globe. Higher transmissibility and immunologic resistance of VOCs bring unprecedented ...
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New vision on the new era of genome study
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Kinetics study of the natural split Npu DnaE intein in the generation of bispecific IgG antibodies
Rapid and efficient bispecific antibody (BsAb) production for industrial applications is still facing many challenges. We reported a technology platform for generating bispecific IgG antibodies, “Bispecific An...
