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    Article

    A drug-tunable Flt23k gene therapy for controlled intervention in retinal neovascularization

    Gene therapies that chronically suppress vascular endothelial growth factor (VEGF) represent a new approach for managing retinal vascular leakage and neovascularization. However, constitutive suppression of VE...

    **ying Chen, Fan-Li Lin, Jacqueline Y. K. Leung, Leilei Tu, Jiang-Hui Wang in Angiogenesis (2021)

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    Article

    AAV-mediated gene delivery of the calreticulin anti-angiogenic domain inhibits ocular neovascularization

    Ocular neovascularization is a common pathological feature in diabetic retinopathy and neovascular age-related macular degeneration that can lead to severe vision loss. We evaluated the therapeutic efficacy of...

    Leilei Tu, Jiang-Hui Wang, Veluchamy A. Barathi, Selwyn M. Prea, Zheng He in Angiogenesis (2018)