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  1. Article

    Open Access

    Caspase-2 impacts lung tumorigenesis and chemotherapy response in vivo

    Caspase-2 is an atypical caspase that regulates apoptosis, cell cycle arrest and genome maintenance, although the mechanisms are not well understood. Caspase-2 has also been implicated in chemotherapy response...

    M R Terry, R Arya, A Mukhopadhyay, K C Berrett, P M Clair in Cell Death & Differentiation (2015)

  2. No Access

    Chapter and Conference Paper

    High-dose Therapy and Autografting with Mobilized Peripheral Blood Progenitor Cells in Patients with Malignant Lymphoma

    In this report we present the data of 100 patients who were autografted with peripheral blood progenitor cells (PBPC) following high-dose conditioning therapy. Fifty-six patients were male and 44 were female w...

    R. Haas, H. Goldschmidt, R. Möhle, S. Frühauf, S. Hohaus, B. Witt in Acute Leukemias V (1996)

  3. No Access

    Article

    Detection of minimal tumor load in blood stem cell autografts in multiple myeloma: Steady-state versus high-dose chemotherapy stem cell mobilization

    H. Goldschmidt, M. Moos, F. Cremer in Journal of Cancer Research and Clinical On… (1995)

  4. No Access

    Chapter and Conference Paper

    Autologous Transplantation with Mafosfamide-Purged Bone Marrow for Acute Myelogenous Leukemia in First and Second Complete Remission

    Despite improvements in the conventional treatment of adult patients with acute myelogenous leukemia (AML) the probability of Gontinuous CR ranges from 8% to 45% at 3 years [1]. Intensive consolidation therapy...

    R. Haas, R. Ehrhardt, G. Boschmann, B. Witt, H. Döhner, M. Körbling in Acute Leukemias IV (1994)

  5. No Access

    Chapter and Conference Paper

    Idarubicin/Cytosine Arabinoside and Mitoxantrone/Etoposide with rhGM-CSF Priming for De Novo Acute Myelogenous Leukemia

    With conventional induction chemotherapy 60 to 70% of adult patients with acute myelogenous leukemia (AML) achieve complete remission (CR) [1]. Chemotherapeutic protocols for induction treatment mainly consist...

    R. Haas, H. Döhner, R. Ehrhardt, H. Goldschmidt, B. Witt, H. Huberts in Acute Leukemias IV (1994)

  6. No Access

    Chapter

    Mobilization of Blood Stem Cells with Recombinant Human (rh)G-CSF in Patients with Hematological Malignancies and Solid Tumors

    Peripheral blood stem cells (PBSC) are being increasingly used for autografting in patients with malignant diseases to circumvent the myelotoxic effects of high-dose therapy [1]. It is generally accepted that ...

    R. Haas, S. Hohaus, R. Ehrhardt, H. Goldschmidt in Peripheral Blood Stem Cell Autografts (1993)

  7. No Access

    Chapter and Conference Paper

    Autologous Bone Marrow Transplantation in Patients with Acute Lymphoblastic Leukemia in Second or Subsequent Complete Remission

    With intensive conventional chemotherapy a complete remission (CR) can be achieved in more than 90% of children and 70% of adults with ALL [l].The long-term disease-free survival for patients with ALL depends ...

    R. Haas, B. Dörken, E. Ogniben, S. Hohaus, B. Witt, G. Kvalheim in Acute Leukemias (1992)

  8. No Access

    Chapter and Conference Paper

    Autologous Transplantation of Blood Stem Cells Mobilized with Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor Subsequent to Chemotherapy for Relapsed Hodgkin’s Disease

    High-dose chemotherapy alone or combined with total body irradiation followed by autologous bone marrow transplantation improves disease-free survival for patients with hematological malignancies and solid tum...

    R. Haas, S. Hohaus, A. Schneeweiß in Cytokines in Hemopoiesis, Oncology, and AI… (1992)

  9. No Access

    Chapter and Conference Paper

    Induction Therapy for Acute Myelogenous Leukemia with Idarubicin/Cytosine Arabinoside and Mitoxantrone/Etoposide in “Response-Adapted” Sequence

    With conventional induction chemotherapy 47%–72% of adult patients with acute myelogenous leukemia (AML) achieve complete remission (CR). However, the probability of continuous CR ranges from 8% to 45% at 3 ye...

    R. Haas, A. Schneeweiß, B. Brado, B. Witt, W. Hunstein, F. Del Valle in Acute Leukemias (1992)

  10. Article

    Abstract

    Ch. Mache, Ch. Urban, H. Sauer, G. Brandesky, H. Meßner in Annals of Hematology (1992)