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  1. No Access

    Article

    In vitro generation of mature, naive antigen-specific CD8+ T cells with a single T-cell receptor by agonist selection

    Peripheral blood T cells transduced with a tumor-specific T-cell receptor (TCR) face problems of auto-reactivity and lack of efficacy caused by cross-pairing of exogenous and endogenous TCR chains, as well as ...

    S Snauwaert, G Verstichel, S Bonte, G Goetgeluk, S Vanhee, Y Van Caeneghem… in Leukemia (2014)

  2. No Access

    Article

    Notch induces human T-cell receptor γδ+ thymocytes to differentiate along a parallel, highly proliferative and bipotent CD4 CD8 double-positive pathway

    In wild-type mice, T-cell receptor (TCR) γδ+ cells differentiate along a CD4 CD8 double-negative (DN) pathway whereas TCRαβ+ cells differentiate along the double-positive (DP) pathway. In the human postnatal thym...

    S Van Coppernolle, S Vanhee, G Verstichel, S Snauwaert, A van der Spek… in Leukemia (2012)

  3. No Access

    Chapter

    27 Klinisch onderzoek bij ademgeur

    Ademgeur komt bij meer dan de helft van de bevolking voor en dan vooral ’s morgens (Courtois, 1986). Een slecht riekende adem komt op alle leeftijden voor en even vaak bij mannen als bij vrouwen. Velen die te ...

    B. Vandekerckhove, D. van Steenberghe in Parodontologie (2009)

  4. No Access

    Chapter

    45 Ademgeurtherapie

    Ademgeur kan worden veroorzaakt door meestal intra-, maar ook verschillende extraorale factoren. De frequentste hiervan zijn keel-neus-ooraandoeningen en systemische ziekten, zoals diabetes mellitus, uremie,le...

    B. Vandekerckhove, J. Poelmans, D. van Steenberghe in Parodontologie (2009)

  5. No Access

    Chapter

    32 Chemische plaquebeheersing

    De meest frequente infecties in de mondregio zijn cariës en parodontitis. Deze aandoeningen zijn geassocieerd met plaque. Voor parodontitis zijn we aangewezen op de voortdurende verwijdering van de bacteriële ...

    B. Vandekerckhove in Parodontologie (2009)

  6. No Access

    Article

    Human intrathymic development: a selective approach

    Human T lymphocytes can be generated from CD34 progenitor cells from different sources. This can be obtained in an in vivo model wherein human thymic tissue and fetal liver is transplanted in an immunodeficien...

    J. Plum, M. De Smedt, G. Leclercq, T. Taghon, T. Kerre… in Seminars in Immunopathology (2008)

  7. Article

    Open Access

    Multicentre, prospective, open study to evaluate the safety and efficacy of hylan G-F 20 in knee osteoarthritis subjects presenting with pain following arthroscopic meniscectomy

    The aim of the study was to evaluate the safety and efficacy of viscosupplementation with hylan G-F 20 in patients with mild to moderate osteoarthritis (OA) presenting with persistent knee pain 4–12 weeks afte...

    J. P. Huskin, B. Vandekerckhove, P. Delincé… in Knee Surgery, Sports Traumatology, Arthros… (2008)

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  8. No Access

    Article

    The safety and efficacy of a powered toothbrush on soft tissues in patients with implant-supported fixed prostheses

    The safety, efficacy and acceptability of an oscillating/rotating powered toothbrush was assessed in patients rehabilitated with fixed prostheses on implants. One hundred consecutive patients (aged 18–80; mean...

    B. Vandekerckhove, M. Quirynen, P. R. Warren, J. Strate… in Clinical Oral Investigations (2004)