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Article
Open AccessFGFR1 inhibition in lung squamous cell carcinoma: questions and controversies
Although the incidence of lung cancer has decreased due to the reduction of tobacco use, lung cancer remains the leading cause of cancer-related death. Lung squamous cell carcinoma represents 30% of lung cance...
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Article
Open AccessFrequency and prognostic significance of p16INK4A protein overexpression and transcriptionally active human papillomavirus infection in laryngeal squamous cell carcinoma
Human papillomavirus (HPV) infection is a powerful prognostic biomarker in a subset of head and neck squamous cell carcinomas, specifically oropharyngeal cancers. However, the role of HPV in non-oropharyngeal ...
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Article
Thromboprophylaxis for lung cancer patients—multimodality assessment of clinician practices, perceptions and decision support tools
The purpose of this study was to report the opinions and self-reported practices of clinicians, as well as the availability of decision support tools, regarding appropriate thromboprophylaxis for patients with...
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Article
832 L-6 in Children with Reactive Thrombocytosis
Background: Reactive thrombocytosis is associated with a variety of clinical conditions such as respiratory tract infections and iron deficiency anemia. IL-6 stimulates the release CRP. IL-6 stimulates thrombo...
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Article
Open AccessA phase I trial of high-dose palliative radiotherapy plus concurrent weekly Vinorelbine and Cisplatin in patients with locally advanced and metastatic NSCLC
The role of concurrent chemoradiotherapy (CRT) in patients with non-small-cell lung cancer (NSCLC) unsuitable for radical therapy but who require locoregional treatment has not been defined. The aims of this p...
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Chapter and Conference Paper
Towards Diagnosis and Treatment of Alzheimer’s Disease
More and more evidence shows that Alzheimer’s disease belongs to the family of conformational diseases characterized by protein self-association and tissue deposition as amyloid fibrils. As recently shown, mon...
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Article
Skew loops and quadric surfaces
A skew loop is a closed curve without parallel tangent lines. We prove: The only complete surfaces in R 3 with a point of positive curvature and no skew loops are the quadrics. In particular: Ellipsoids are th...
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Chapter and Conference Paper
Generation and brain delivery of anti-aggregating antibodies against β-amyloid plaques using phage display technology
Antibodies towards the N-terminal region of the (β-amyloid peptide bind to β-amyloid fibrils, leading to their disaggregation. We generated anti-aggregating (β-amyloid antibodies using filamentous phages displ...
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Article
Predictive value of hCG level 14 days after embryo transfer
It has been reported that the quantitative serum hCG level 14 days after embryo transfer (ET) correlated with pregnancy outcome as well as a likelihood of a multiple gestation pregnancy. This prospective study.....
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Chapter and Conference Paper
Starch hydrolysis by immobilized enzymes industrial applications
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Article
Flavin-protein interaction in bound glucose oxidase
Glucose oxidase was bound to Sepharose, Sephadex, gelatin, and dextran, yielding immobilized soluble and insoluble derivatives of the enzyme. The soluble preparations possessed higher enzymic activity than the...
