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Article
Indoor climate and air quality in new offices: effects of a reduced air-exchange rate
In response to a request from the personnel of a credit bank that had been moved into a new building, an evaluation was made of employee health complaints. The prevalence of symptoms was determined using a sel...
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Article
Relationships Between Debrisoquine Hydroxylation and Propafenone Pharmacokinetics
The aims of this study were to evaluate the oxidising phenotype in a random sample of the Italian population and to study the relationships between the phenotype and the pharmacokinetics of propafenone, which ...
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Chapter
In Vivo Effects of Dermatan Sulfate After Intravenous Injection in Calcium-Oxalate Stone Formers
Several reports have suggested that glycosaminoglycans (GAG) inhibit the formation of calcium-containing stones through their restraining effects on growth and aggregation of calcium-oxalate (CaOx) crystals (1...
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Article
Effects of modifiers on the chromatographic behaviour of propafenone and its major metabolites
Propafenone (PPF) is a new antiarrhythmic agent with structural features in common with the class of beta-blocking drugs (phenoxypropanolamines). Because of its high lipophilicity, the drug is strongly retaine...
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Article
Antiarrhythmic efficacy of propafenone: Evaluation of effective plasma levels following single and multiple doses
In 11 patients with stable premature ventricular beats, the kinetics of single (150 and 300 mg) and multiple (150 mg t.i.d. and 300 mg t.i.d.) oral doses of propafenone were studied with reference to arrhythmi...
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Chapter and Conference Paper
Urinary Excretion Pattern of Main Glycosaminoglycans in Stone Formers and Controls
Various inhibitors of calcium oxalate (CaOx) crystal growth and aggregation have been found in human urine. These findings led to the hypothesis that a deficiency of these substances may be involved in the gen...
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Chapter and Conference Paper
Excretion Pattern of Isomeric Chondroitin Sulphates in Stone-Forming Subjects and Controls
Calcium oxalate (CaOx) stone formation depends on both oversaturation with CaOx and the level of inhibitory activity that retards the crystallization of the salt. Robertson et al. (1) showed that naturally occ...
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Article
Comparison of Antihypertensive Efficacy of Atenolol, Oxprenolol and Pindolol at Rest and during Exercise
The importance of cardioselectivity and partial agonist activity (PAA) of β-blockers in controlling blood pressure is under debate. This study was designed to compare the anti-hypertensive effect of a long-act...
