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Article
Cardiovascular disease risk, vascular health and erectile dysfunction among middle-aged, clinically depressed men
Erectile dysfunction (ED) is especially common in men with major depressive disorder (MDD). This study examined the extent to which risk factors for cardiovascular disease (CVD) and vascular endothelial dysfun...
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Article
The ups and downs of Feher-style ENDOR
A new transient variation of the “Feher-style” electron-nuclear double resonance (ENDOR) method is examined. In this technique, the passage-mode electron paramagnetic resonance (EPR) signal is monitored follow...
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Article
Investigation by EPR and ENDOR spectroscopy of the novel 4Fe ferredoxin fromPyrococcus furiosus
The hyperthermophilic archaeonPyrococcus furiosus contains a four-Fe ferredoxin (Pf- Fd) that differs from most other 4Fe-Fd’s in that its [Fe4S4] cluster is anchored to protein by only three cysteinyl residues.P...
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Chapter
CO Binding to and Metal-Ion Valencies of the Femo-Cofactor in CO-Inhibited Nitrogenase
When Mo-nitrogenase undergoes enzymatic turnover in the presence of CO, the S = 3/2 cofactor signal is replaced by two different S = 1/2 signals, one (lo-CO; g = 2.09, 1.97, 1.93) at low pressure (0.08 atm) and t...
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Article
Activity of trovafloxacin against blood isolates ofStreptococcus pneumoniae in Sweden
The in vitro activity of the fluoroquinolone trovafloxacin (CP-99,219) against 257 blood isolates ofStreptococcus pneumoniae obtained from Swedish hospitals was compared with those of commonly prescribed oral ant...
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Article
Ligand Substitution Effect on Optical Properties in Conducting Tetraazaporphyrines
Self-consistent Density Functional calculations have been performed on a variety of planar conjugated Ni-centered macrocycles with a basic tetraazaporphyrinic core and dithiolene groups (PZ) or fused-benzo gro...
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Chapter
Cytochrome c Oxidase: A Brief Introduction and Some New Results from High Field Endor Studies of The CuA and CuB Sites
A Mitchellian view of mitochondrial respiration is presented in Scheme I.1,2 This illustrates electron transfer from an electron rich material, NH, through quinone, Q, through Complex HI, into cytochrome c, and t...
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Chapter and Conference Paper
Endor of Metalloproteins at X-Band and Q-Band Microwave Frequencies
One of the common difficulties in the ENDOR studies of many metalloproteins is that the resonances of non-protonic elements in the site of interest frequently are obscured by the more intense proton ENDOR sign...