25 Result(s)

Article

Single nucleotide polymorphisms in genes that are associated with a modified response to statin therapy: the Rotterdam Study

The objective of this study was to investigate whether common variation in genes involved in lipid metabolism modify the effect of statins on serum total cholesterol concentration. Statin users were identified...

C E de Keyser, M Eijgelsheim, A Hofman, E J G Sijbrands… in The Pharmacogenomics Journal (2011)

Article

Interaction between polymorphisms in the renin–angiotensin–system and angiotensin-converting enzyme inhibitor or β-blocker use and the risk of myocardial infarction and stroke

This study investigates whether the interaction between angiotensin-converting enzyme (ACE) inhibitors or β-blockers and the ACE insertion/deletion (I/D) polymorphism or angiotensin receptor II type 1 (AGTR1) ...

H Schelleman, O H Klungel, J C M Witteman, M M B Breteler… in The Pharmacogenomics Journal (2008)

Article

Diuretic–gene interaction and the risk of myocardial infarction and stroke

This study investigates whether the interaction between diuretics and alpha-adducin (ADD1) G460W or G-protein β3-subunit (GNB3) rs2301339 polymorphism modifies the risk of myocardial infarction (MI) or stroke. Da...

H Schelleman, O H Klungel, J C M Witteman, M M B Breteler… in The Pharmacogenomics Journal (2007)

Article

Differential Roles of Angiotensinogen and Angiotensin Receptor type 1 Polymorphisms in Breast Cancer Risk

While angiotensinogen (AGT) seems to have anti proliferative properties, angiotensin II (ATII) is a potent growth factor and it mediates its actions through the angiotensin type 1 receptor (AGTR1). In the AGT ...

A. M. González-Zuloeta Ladd, A. Arias Vásquez… in Breast Cancer Research and Treatment (2007)

Article

Interleukin 6 G−174 C polymorphism and breast cancer risk

Interleukin-6 (IL-6) is a growth factor involved in many processes including carcinogenesis. The C allele of the G−174 C promoter single nucleotide polymorphism (SNP) in the IL-6 gene decreases levels of IL-6 ...

A. M. González-Zuloeta Ladd, A. Arias Vásquez… in European Journal of Epidemiology (2006)

Article

Interactions between five candidate genes and antihypertensive drug therapy on blood pressure

Despite the availability of effective antihypertensive drugs, there is a large variation in response to these drugs. This study investigates whether polymorphisms in the angiotensin converting enzyme (I/D), an...

H Schelleman, B H Ch Stricker, W M M Verschuren, A de Boer… in The Pharmacogenomics Journal (2006)

Article

Repeated nitrate prescriptions as a potential marker for angina pectoris A comparison with medical information from the Rotterdam Study

Objective: The objective of this study was to determine whether pharmacy records of nitrate prescriptions could be used as a marker of angina pectoris.Method: This study was conducted within the Rotterdam Study,...

A.H. Maitland‐van der Zee, O.H. Klungel, H.G.M. Leufkens… in Pharmacy World and Science (2003)

Article

Commentary: Drug safety epidemiology: Time for Europe to start using this instrument

B.H.Ch. Stricker in European Journal of Epidemiology (2003)

Article

Utilisation of malaria prophylaxis: the effect of changes in guidelines in the Netherlands, 1993‐1998

Introduction: The increase in international travelling from temperate zones to tropical countries and increasing drug resistance of Plasmodium falciparum has resulted in a growing number of travellers that are a...

M.M. van Riemsdijk, M.C.J.M. Sturkenboom, H.J. Schilthuis… in Pharmacy World and Science (2003)

Article

Evaluation of antiparkinsonian drugs in pharmacy records as a marker for Parkinson's disease

Aim: The aim of this study was to determine whether use of antiparkinsonian drugs in pharmacy records can be used as a marker for patients with Parkinson's disease (PD). Method: Data were obtained from the Rotte...

D.A.M.C. van de Vijver, A.J. Porsius, A. de Boer… in Pharmacy World and Science (2001)

Article

Fluoroquinolone use and the change in incidence of tendon ruptures in the Netherlands

Introduction: Shortly after their introduction, fluoroquinolones were associated with reports of tendinitis and tendon rupture. During the past years, the number of reports has risen, possibly because of an incr...

P.D. van der Linden, B.H.Ch Stricker, H.G.M. Leufkens… in Pharmacy World and Science (2001)

Article

Cough due to ace inhibitors: a case-control study using automated general practice data

Objectives: To determine the risk of coughing as an adverse reaction to ACE inhibitors under everyday circumstances in a large population, and to study whether this adverse effect was duration or dose dependent.

L. E. Visser, B. H. Ch. Stricker, A. E. Vlug… in European Journal of Clinical Pharmacology (1996)

Article

Abstracts of papers and posters

C. C. M. Veninga, P. Denig, F. M. Haaijer-Ruskamp… in Pharmacy World and Science (1995)

Article

Abstracts of papers and posters Meeting on Pharmaceutical Sciences

Russell C. Coile Jr., K. Wiedhaup, Ilva van Bommel… in Pharmacy World and Science (1993)