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Open AccessVOLT: a novel open-source pipeline for automatic segmentation of endolymphatic space in inner ear MRI
Objective and volumetric quantification is a necessary step in the assessment and comparison of endolymphatic hydrops (ELH) results. Here, we introduce a novel tool for automatic volumetric segmentation of the...
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Article
A probabilistic atlas of the human inner ear’s bony labyrinth enables reliable atlas-based segmentation of the total fluid space
Intravenous contrast agent-enhanced magnetic resonance imaging of the endolymphatic space (ELS) of the inner ear permits direct, in-vivo, non-invasive visualization of labyrinthine structures and thus verifica...
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Article
Comparison of 18F-GE-180 and dynamic 18F-FET PET in high grade glioma: a double-tracer pilot study
PET represents a valuable tool for glioma imaging. In addition to amino acid tracers such as 18F-FET, PET targeting the 18-kDa mitochondrial translocator-protein (TSPO) is of high interest for high-grade glioma (...
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Article
High-resolution MRI of the inner ear enables syndrome differentiation and specific treatment of cerebellar downbeat nystagmus and secondary endolymphatic hydrops in a postoperative ELST patient
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Transient endolymphatic hydrops after an attack of vestibular migraine: a longitudinal single case study
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TSPO PET with [18F]GE-180 sensitively detects focal neuroinflammation in patients with relapsing–remitting multiple sclerosis
Expression of the translocator protein (TSPO) is upregulated in activated macrophages/microglia and is considered to be a marker of neuroinflammation. We investigated the novel TSPO ligand [18F]GE-180 in patients...
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Article
Vestibular and visual cortex activity during room tilt illusion
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Article
Resting-state global functional connectivity as a biomarker of cognitive reserve in mild cognitive impairment
Cognitive reserve (CR) shows protective effects in Alzheimer’s disease (AD) and reduces the risk of dementia. Despite the clinical significance of CR, a clinically useful diagnostic biomarker of brain changes ...
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Article
Clinical features of delayed endolymphatic hydrops and intralabyrinthine schwannoma
The aim of this study was to compare the clinical history and audiovestibular function test results of patients suffering from intralabyrinthine schwannoma or delayed endolymphatic hydrops (DEH).
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Erratum to: The PROMESA-protocol: progression rate of multiple system atrophy under EGCG supplementation as anti-aggregation-approach
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Structural and functional connectivity map** of the vestibular circuitry from human brainstem to cortex
Structural and functional interconnections of the bilateral central vestibular network have not yet been completely delineated. This includes both ipsilateral and contralateral pathways and crossing sites on t...
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Article
MR volumetric assessment of endolymphatic hydrops
We aimed to volumetrically quantify endolymph and perilymph spaces of the inner ear in order to establish a methodological basis for further investigations into the pathophysiology and therapeutic monitoring o...
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Article
Dual-energy CT Immediately after Endovascular Stroke Intervention: Prognostic Implications
Posttreatment intracerebral hemorrhage (ICH) after recanalization therapy of acute ischemic stroke increases morbidity and mortality. Dual-energy (DE) computed tomography (CT) allows differentiation of blood–b...
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Article
The autism brain imaging data exchange: towards a large-scale evaluation of the intrinsic brain architecture in autism
Autism spectrum disorders (ASDs) represent a formidable challenge for psychiatry and neuroscience because of their high prevalence, lifelong nature, complexity and substantial heterogeneity. Facing these obsta...
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Article
Treatment of astrocytoma grade III with Photofrin II as a radiosensitizer
Astrocytomas are neoplasms that originate from glial cells. Anaplastic astrocytoma is classified as WHO III, with 27 % of the individuals with grade III astrocytoma living for at least 5 years even after treat...
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Article
Effect of standard-dose Betahistine on endolymphatic hydrops: an MRI pilot study
This study aimed to assess whether standard-dose Betahistine (48 mg daily) exerts an effect upon the degree of endolymphatic hydrops in patients with Menière’s disease using a retrospective case series in the ...
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Acute Neurovascular Events: Bleeding and Ischemia Diagnosed by MSCT
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Application of Photofrin II as a specific radiosensitising agent in patients with bladder cancer—a report of two cases
Background: the effect of ionizing radiation on tumour tissues can be optimised by adding radiosensitising agents to enhance tumour inactivation. Photofrin II has been approved as a photosensitising agent for ...
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Article
Low field–low cost: Can low-field magnetic resonance systems replace high-field magnetic resonance systems in the diagnostic assessment of multiple sclerosis patients?
As low-field MR imaging is becoming a widely used imaging technique, we aimed at a prospective assessment of differences in imaging quality between low- and high-field MR imaging in multiple sclerosis patient...
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Article
Bilateral basal ganglion haemorrhage in diabetic ketoacidotic coma: case report
We report bilateral oedema and haemorrhagic transformation in the basal ganglia of a 59-year old woman with severe diabetic ketoacidosis. Lack of cerebral vascular autoregulation, followed by blood-brain barr...