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Open AccessVOLT: a novel open-source pipeline for automatic segmentation of endolymphatic space in inner ear MRI
Objective and volumetric quantification is a necessary step in the assessment and comparison of endolymphatic hydrops (ELH) results. Here, we introduce a novel tool for automatic volumetric segmentation of the...
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Article
A probabilistic atlas of the human inner ear’s bony labyrinth enables reliable atlas-based segmentation of the total fluid space
Intravenous contrast agent-enhanced magnetic resonance imaging of the endolymphatic space (ELS) of the inner ear permits direct, in-vivo, non-invasive visualization of labyrinthine structures and thus verifica...
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Comparison of 18F-GE-180 and dynamic 18F-FET PET in high grade glioma: a double-tracer pilot study
PET represents a valuable tool for glioma imaging. In addition to amino acid tracers such as 18F-FET, PET targeting the 18-kDa mitochondrial translocator-protein (TSPO) is of high interest for high-grade glioma (...
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High-resolution MRI of the inner ear enables syndrome differentiation and specific treatment of cerebellar downbeat nystagmus and secondary endolymphatic hydrops in a postoperative ELST patient
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Transient endolymphatic hydrops after an attack of vestibular migraine: a longitudinal single case study
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TSPO PET with [18F]GE-180 sensitively detects focal neuroinflammation in patients with relapsing–remitting multiple sclerosis
Expression of the translocator protein (TSPO) is upregulated in activated macrophages/microglia and is considered to be a marker of neuroinflammation. We investigated the novel TSPO ligand [18F]GE-180 in patients...
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Bildgebung des lokal fortgeschrittenen Prostatakarzinoms
Das Prostatakarzinom (PCa) ist der in Deutschland häufigste maligne Tumor des Mannes und stellt damit besondere Ansprüche an eine differenzierte Bildgebung und risikoadaptierte Therapieansätze. Die multiparame...
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Vestibular and visual cortex activity during room tilt illusion
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MRT der Prostata
Neue klinische und technische Entwicklungen auf dem Gebiet der Magnetresonanztomographie (MRT) und gezielter bildgestützter Biopsietechniken haben die Detektion, die Lokalisation, das Staging sowie die aktive ...
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Resting-state global functional connectivity as a biomarker of cognitive reserve in mild cognitive impairment
Cognitive reserve (CR) shows protective effects in Alzheimer’s disease (AD) and reduces the risk of dementia. Despite the clinical significance of CR, a clinically useful diagnostic biomarker of brain changes ...
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Article
Clinical features of delayed endolymphatic hydrops and intralabyrinthine schwannoma
The aim of this study was to compare the clinical history and audiovestibular function test results of patients suffering from intralabyrinthine schwannoma or delayed endolymphatic hydrops (DEH).
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Klinische Eigenschaften von „delayed endolymphatic hydrops“ und intralabyrinthärem Schwannom
Ziel der Studie war es, die Krankengeschichte und die Befunde in audiovestibulären Funktionsuntersuchungen bei Patienten mit intralabyrinthärem Schwannom oder „delayed endolymphatic hydrops“ (DEH) zu vergleichen.
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Erratum to: The PROMESA-protocol: progression rate of multiple system atrophy under EGCG supplementation as anti-aggregation-approach
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Hydropische Ohrerkrankung vom vestibulären Typ
Wir berichten über einen Patienten mit rezidivierenden Drehschwindelattacken über Jahre. Ohrsymptome wurden verneint. Die klinische Diagnose war unklar. M. Menière, die vestibuläre Migräne und rezidivierender ...
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Structural and functional connectivity map** of the vestibular circuitry from human brainstem to cortex
Structural and functional interconnections of the bilateral central vestibular network have not yet been completely delineated. This includes both ipsilateral and contralateral pathways and crossing sites on t...
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MR volumetric assessment of endolymphatic hydrops
We aimed to volumetrically quantify endolymph and perilymph spaces of the inner ear in order to establish a methodological basis for further investigations into the pathophysiology and therapeutic monitoring o...
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Dual-energy CT Immediately after Endovascular Stroke Intervention: Prognostic Implications
Posttreatment intracerebral hemorrhage (ICH) after recanalization therapy of acute ischemic stroke increases morbidity and mortality. Dual-energy (DE) computed tomography (CT) allows differentiation of blood–b...
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Article
The autism brain imaging data exchange: towards a large-scale evaluation of the intrinsic brain architecture in autism
Autism spectrum disorders (ASDs) represent a formidable challenge for psychiatry and neuroscience because of their high prevalence, lifelong nature, complexity and substantial heterogeneity. Facing these obsta...
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Hereditäre diffuse Leukenzephalopathie mit Sphäroiden
Die hereditäre diffuse Leukenzephalopathie mit Sphäroiden (HDLS) stellte aufgrund der vielfältigen Symptomatik der Patienten und der unklaren Pathophysiologie bislang nur ein vages Konzept dar. Auch die Neurop...
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Article
Treatment of astrocytoma grade III with Photofrin II as a radiosensitizer
Astrocytomas are neoplasms that originate from glial cells. Anaplastic astrocytoma is classified as WHO III, with 27 % of the individuals with grade III astrocytoma living for at least 5 years even after treat...