Skip to main content

5 Result(s)

within B. E. Tuch Remove this filter

and

  1. Article

    TNF-related apoptosis-inducing ligand (TRAIL) protects against diabetes and atherosclerosis in Apoe −/− mice

    TNF-related apoptosis-inducing ligand (TRAIL) is implicated in the regulation of diabetes and is reduced in patients with cardiovascular disease. Although TRAIL receptors are widespread, and TRAIL can promote ...

    B. A. Di Bartolo, J. Chan, M. R. Bennett, S. Cartland, S. Bao, B. E. Tuch… in Diabetologia (2011)

    Download PDF (461 KB) View Article

  2. No Access

    Article

    Function of a genetically modified human liver cell line that stores, processes and secretes insulin

    An alternative approach to the treatment of type I diabetes is the use of genetically altered neoplastic liver cells to synthesize, store and secrete insulin. To try and achieve this goal we modified a human l...

    B E Tuch, B Szymanska, M Yao, M T Tabiin, D J Gross, S Holman, M Anne Swan… in Gene Therapy (2003)

  3. Article

    Mechanisms of arginine-induced increase in cytosolic calcium concentration in the beta-cell line NIT-1

    The effects of l-arginine and its analogues NG-nitro-l-arginine, NG-methyl-l-arginine, l-homoarginine and d-arginine on cytosolic calcium concentration were investigated to characterise the mechanisms of arginin...

    A. J. Weinhaus, P. Poronnik, B. E. Tuch, D. I. Cook in Diabetologia (1997)

    Download PDF (223 KB)

  4. Article

    Streptozotocin is not toxic to the human fetal B cell

    It has been generally assumed that because streptozotocin is toxic to the adult B cell of most species, it should also damage B cells obtained at earlier stages of development. This paper examines whether this...

    B. E. Tuch, J. R. Turtle, C. J. Simeonovic in Diabetologia (1989)

    Download PDF (1309 KB)

  5. Article

    Maturation of the response of human fetal pancreatic expiants to glucose

    The release of insulin from the human pancreas in response to glucose is known to be either poor or absent in the fetus, whereas in the infant and adult, the response is much greater. The maturation of this re...

    B. E. Tuch, A. Jones, J. R. Turtle in Diabetologia (1985)

    Download PDF (427 KB)