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Article
ECMO-Therapie beim akuten Lungenversagen
In der Intensivmedizin erleben wir rasante technische Fortschritte, die in vielen Fällen vorteilhaft für unsere Patienten sind. Auf der anderen Seite werden aber auch Stimmen laut, die generell einen zunehmend...
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Article
Pneumologische Notfälle bei Kollagenosen und Vaskulitiden
Pneumologische Notfälle in der Rheumatologie sind seltene, im Einzelfall lebensbedrohliche Krankheitsbilder, die bei Patienten mit entzündlichen rheumatischen Systemerkrankungen als Komplikation der Grunderkra...
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Article
Kommt die Lungenkrebs-Früherkennung mit CT?
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Article
Systematic expression profiling of innate immune genes defines a complex pattern of immunosenescence in peripheral and intestinal leukocytes
Immunosenescence is characterized by a quantitative decline of adequate immune responses, which renders the elderly individual particularly susceptible to bacterial, viral and fungal pathogens. Whereas changes...
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Article
Activation of the hypothalamo-pituitary-adrenal axis in response to septic or non-septic diseases – implications for the euthyroid sick syndrome
Objective: To determine whether cytokine release or activation of the hypothalamo-pituitary-adrenal (HPA) axis is predominantly involved in the development of the euthyroid sick syndrome (ESS). Design: Prospectiv...
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Article
Eosinophilic alveolitis in BAL after lung transplantation
Lung transplantation has become a therapeutic option for patients with end stage lung disease. However, outcome after transplantation is complicated by episodes of rejection and infections. Bronchoalveolar la...
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Article
Inhibition of adenovirus-mediated gene transfer by bronchoalveolar lavage fluid
Human and animal trials with recombinant adenovirus have been discouraging, since the level of recombinant gene expression was low. Nonspecific and specific immune response mediated by, for example, macrophage...
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Article
Alveolar macrophages from bronchoalveolar lavage of patients with pulmonary histiocytosis X: Determination of phenotypic and functional changes
In recent years the alveolar macrophage has been found to play a central role in interstitial lung disease. Pulmonary histiocytosis X is characterized by infiltrating fibroblasts, mononuclear cells, and CD-1-p...
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Article
Inhibitory effects of inhaled flunisolide on inflammatory functions of alveolar macrophages
We have studied 15 patients with slight or moderate bronchial obstruction, all of whom were being treated by inhalation of the β-mimetic fenoterol 4×400 μg/day, and 7 of whom were also receiving inhaled flunis...