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Anticancer and Interferon Agents: Synthesis and Properties - Drugs and Parmacutical Sciences - Vol. 24

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  1. Article

    Open Access

    Evaluation of rodent-only toxicology for early clinical trials with novel cancer therapeutics

    Preclinical toxicology studies are performed prior to phase I trials with novel cancer therapeutics to identify a safe clinical starting dose and potential human toxicities. The primary aim of this study was t...

    D R Newell, S S Burtles, B W Fox, D I Jodrell, T A Connors in British Journal of Cancer (1999)

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