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Article
Open AccessSafety and outcome of definitive chemoradiotherapy in elderly patients with oesophageal cancer
Little is known about chemoradiotherapy (CRT) in elderly patients with a locally advanced oesophageal cancer (OC). The aim of our study was to evaluate the tolerance and the outcome of elderly patients older t...
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Article
Open AccessClinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy
The predictive value of KRAS mutation in metastatic colorectal cancer (MCRC) patients treated with cetuximab plus chemotherapy has recently been suggested. In our study, 59 patients with a chemotherapy-refractory...
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Article
Open AccessInduction cisplatin–irinotecan followed by concurrent cisplatin–irinotecan and radiotherapy without surgery in oesophageal cancer: multicenter phase II FFCD trial
A recent phase I study showed that weekly cisplatin, irinotecan and concurrent radiotherapy can be administered with moderate toxicity in patients with oesophageal cancer. Patients with no prior treatment and ...
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Article
Open Access‘A phase II study of oral uracil/ftorafur (UFT®) plus leucovorin combined with oxaliplatin (TEGAFOX) as first-line treatment in patients with metastatic colorectal cancer’
This phase II trial was performed to evaluate the efficacy and tolerability of a new combination of Uracil/Ftorafur (UFT®)/leucovorin (LV) and oxaliplatin in patients (pts) with metastatic colorectal cancer (MCRC...
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Article
Extended necrosis of the oesophageal wall after photodynamic therapy: Report of two cases
Nous rapportons 2 observations de nécrose étendue de l'oesophage après photochimiothérapie par laser à colorant. Dans les 2 cas, le traitement laser était indiqué pour une petite récidive d'un carcinome oesoph...
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Chapter and Conference Paper
The Value of Preoperative Radiotherapy in Esophageal Cancer: Results of a Study by the EORTC
Attempts to combine radiation therapy and surgery in operable patients with carcinoma of the esophagus started 30 years ago. The first reported surgical series showed a low rate of resectability and a high pos...
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Chapter and Conference Paper
Controlled Clinical Trial for the Treatment of Patients with Inoperable Esophageal Carcinoma: A Study of the EORTC Gastrointestinal Tract Cancer Cooperative Group
Radiotherapy is the usual treatment for inoperable esophageal carcinoma. Results published before 1976, when this trial was begun were very modest, except for those of Pearson [1], The 1-year survival rate var...
