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Chapter
Burkitt’s lymphoma: Multiparametric analysis of 55 cell lines with special reference to morphometry
The term ‘Burkitt’s lymphoma’ (BL) connotes a specific morphologic appearance which has been well described [1]. However, the boundaries of this entity from other related B-cell lymphomas, especially the small...
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Chapter and Conference Paper
Conclusions
The evaluation of the management of NHL in Europe shows that many European groups are today in the favourable position of carrying out clinical research competitive with that of the North-American Study Groups...
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Chapter and Conference Paper
Stimulation of Peripheral Blood Progenitor Cells by Chemotherapy and Granulocyte-Macrophage Colony-Stimulating Factor in Lymphoproliferative Diseases
Hematopoietic progenitor cells can be collected from the peripheral blood, cryopreserved, and reinfused after chemotherapy ablation in cancer patients [1]. The advantage of autografting with circulating progen...
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Article
Multivariate analysis of prognostic factors in patients with non HIV-related primary cerebral lymphoma. A proposal for a prognostic scoring
Between 1982 and 1991, 41 patients were treated for non HIV related primary cerebral lymphoma (PCL) in our institute. The purpose of this study was to perform a multivariate analysis of prognostic factors for ...
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Chapter
The management of chronic lymphocytic leukemia — a case history
Chronic lymphocytic leukemia (CLL) is a common lymphoproliferative disease. In Western countries, CLL is the leukemia with the highest incidence among persons aged 50 to 55 years and older. Hallmarks of the di...
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Chapter and Conference Paper
Follicular Lymphomas: Morphology, Prognostic Factors and Treatment
Meaningful discussion of therapy of a disease requires a precise definition of the pathologic entity needing therapy. This requirement is only partially fulfilled for the non-Hodgkin’s lymphomas (NHL). Classif...
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Chapter and Conference Paper
Alpha-Interferon Role in the Management of Follicular Lymphoma Patients. The GELA Experience
Follicular lymphomas (FL) represent between 20 and 25% of all lymphomas and are slightly more frequent in America than in Europe and less frequent in Asia [1]. They are composed of follicle center cells, a mix...
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Article
Plasma levels of tumour necrosis factor and its soluble receptors correlate with clinical features and outcome of Hodgkin's disease patients
A prospective study was performed to assess the use of plasma measurement of tumour necrosis factor (TNF), lymphotoxin alpha (LT alpha) and their soluble receptors (p55 and p75) for prognostic risk assignment ...
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Article
Mantle cell lymphoma: a retrospective study of 121 cases
Mantle cell lymphoma (MCL) patients represent a difficult problem, sometimes to establish the diagnosis but mostly because of their refractoriness to standard lymphoma treatments. Which treatments to apply and...
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Chapter
Risk-related treatment strategies for diffuse large B cell lymphoma
Patients with large cell lymphoma have differing prognoses. Even within a single histologic subtype, outcome is influenced by a number of factors (not all of which are recognized), and the optimal treatment di...
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Chapter
Optimal treatment strategies for peripheral T cell lymphoma (unspecified category)
This review combines peripheral “T cell lymphoma, unspecified”, whatever the cell morphology and the specific variants described in the REAL classification [29.1]. If one is going to identify clinical differen...
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Chapter
Clinical aspects and treatment options of B cell CLL/SLL and immunocytoma
One of the merits of the REAL classification is that it emphasizes different entities and particularly small lymphocytic and lymphoplasmacytic lymphomas. As noted in a preceding chapter, small lymphocytic lymp...
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Article
Translocations involving the short arm of chromosome 17 in chronic B-lymphoid disorders: frequent occurrence of dicentric rearrangements and possible association with adverse outcome
Unbalanced translocations involving chromosome arm 17p, where the TP53 tumor suppressor gene localizes, are rarely described in chronic lymphocytic leukemia and small lymphocytic lymphoma (CLL/SLL), but recent...
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Article
Profiles and prognostic values of LDH isoenzymes in patients with non-Hodgkin’s lymphoma
Serum lactic dehydrogenase (LDH) is an important prognostic factor in patients with non-Hodgkin’s lymphoma (NHL). We have examined the LDH isoenzyme content in serum and CSF of patients with NHL, at diagnosis ...
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Article
A prospective study of intensive induction therapy with high-dose consolidation in patients with aggressive non-Hodgkin's lymphoma and two or three adverse prognostic factors
Patients with nhl and two or three factors of the international prognostic index (ipi) have a poor prognosis. we performed a prospective trial of intensive induction therapy followed with high-dose consolidati...
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Article
Multifocal progressive leukoencephalopathy occurring after refractory anemia and multiple infectious disorders consecutive to severe lymphopenia
Progressive multifocal leukoencephalopathy (PML) is related to central nervous system infection with JC virus (JCV). This leukoencephalopathy occurs in immunocompromised patients such as those with acquired i...
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Article
Identification and validation of seven genes, as potential markers, for the differential diagnosis of small B cell lymphomas (small lymphocytic lymphoma, marginal zone B cell lymphoma and mantle cell lymphoma) by cDNA macroarrays analysis
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Article
Long-term outcome with pentostatin treatment in hairy cell leukemia patients. A French retrospective study of 238 patients
With the introduction of new drugs such as alpha-interferon (IFN) and purine analogs, the management of hairy cell leukemia (HCL) patients has changed. However, deoxycoformycin (DCF) produced higher complete r...
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Article
Open AccessImpact of epoetin β on quality of life in patients with malignant disease
This open-label, prospective study was conducted to compare the impact of epoetin β vs standard care on quality of life (QoL) in anaemic patients with lymphoid or solid tumour malignancies. A total of 262 anaemic...
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Article
FcγRIIB expression in diffuse large B-cell lymphomas does not alter the response to CHOP+rituximab (R-CHOP)