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within B Bossy Remove this filter English Remove this filter Biochemistry, general Remove this filter Cell Cycle Analysis Remove this filter

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  1. Article

    Complex II inhibition by 3-NP causes mitochondrial fragmentation and neuronal cell death via an NMDA- and ROS-dependent pathway

    Mitochondrial respiratory complex II inhibition plays a central role in Huntington's disease (HD). Remarkably, 3-NP, a complex II inhibitor, recapitulates HD-like symptoms. Furthermore, decreases in mitochondr...

    G Liot, B Bossy, S Lubitz, Y Kushnareva, N Sejbuk… in Cell Death & Differentiation (2009)

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  2. Article

    Loss of OPA1 disturbs cellular calcium homeostasis and sensitizes for excitotoxicity

    Optic atrophy 1 ( OPA1 ) mutations cause dominant optic atrophy (DOA) with retinal ganglion cell (RGC) and optic nerve degeneration. The mechanism for the selectiv...

    Y E Kushnareva, A A Gerencser, B Bossy, W-K Ju, A D White… in Cell Death & Differentiation (2013)

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  3. Article

    Cerium oxide nanoparticles protect against Aβ-induced mitochondrial fragmentation and neuronal cell death

    Evidence indicates that nitrosative stress and mitochondrial dysfunction participate in the pathogenesis of Alzheimer’s disease (AD). Amyloid beta (Aβ) and peroxynitrite induce mitochondrial fragmentation and neu...

    J M Dowding, W Song, K Bossy, A Karakoti, A Kumar, A Kim… in Cell Death & Differentiation (2014)

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