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Article
Open AccessCerebellar damage with inflammation upregulates oxytocin receptor expression in Bergmann Glia
The cerebellum plays an important role in cognitive and social functioning. Childhood damage in the cerebellum increases the risk of autism spectrum disorder. Cerebellar inflammation induces social avoidance i...
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Article
Open AccessNanobody-based RFP-dependent Cre recombinase for selective anterograde tracing in RFP-expressing transgenic animals
Transgenic animals expressing fluorescent proteins are widely used to label specific cells and proteins. By using a split Cre recombinase fused with mCherry-binding nanobodies or designed ankyrin repeat protei...
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Article
Open AccessInvolvement of MCH-oxytocin neural relay within the hypothalamus in murine nursing behavior
Multiple sequential actions, performed during parental behaviors, are essential elements of reproduction in mammalian species. We showed that neurons expressing melanin concentrating hormone (MCH) in the later...
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Article
Open AccessNeuronal SIRT1 regulates macronutrient-based diet selection through FGF21 and oxytocin signalling in mice
Diet affects health through ingested calories and macronutrients, and macronutrient balance affects health span. The mechanisms regulating macronutrient-based diet choices are poorly understood. Previous studi...
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Article
Open AccessThe integrative role of orexin/hypocretin neurons in nociceptive perception and analgesic regulation
The level of wakefulness is one of the major factors affecting nociception and pain. Stress-induced analgesia supports an animal’s survival via prompt defensive responses against predators or competitors. Prev...
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Article
Open AccessAtomistic design of microbial opsin-based blue-shifted optogenetics tools
Microbial opsins with a bound chromophore function as photosensitive ion transporters and have been employed in optogenetics for the optical control of neuronal activity. Molecular engineering has been utilize...
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Article
Open AccessVangl2 Regulates E-Cadherin in Epithelial Cells
E-cadherin belongs to the classic cadherin subfamily of calcium-dependent cell adhesion molecules and is crucial for the formation and function of epithelial adherens junctions. In this study, we demonstrate t...
