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    Article

    Telomere maintenance and cancer ? look, no telomerase

    Activation of a telomere maintenance mechanism seems to be indispensable for the immortalization of human cells. Most cancers and cancer cell lines maintain their telomeres via telomerase. In some cancers, how...

    Axel A. Neumann, Roger R. Reddel in Nature Reviews Cancer (2002)

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    Article

    Telomere maintenance by recombination in human cells

    Telomeres of eukaryotic chromosomes contain many tandem repeats of a G-rich sequence (for example, TTAGGG in vertebrates1). In most normal human cells, telomeres shorten with each cell division, and it is propose...

    Melissa A. Dunham, Axel A. Neumann, Clare L. Fasching, Roger R. Reddel in Nature Genetics (2000)