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  1. No Access

    Article

    A hyperthermostable bacterial histone-like protein as an efficient mediator for transfection of eukaryotic cells

    Gene delivery has shown potential in a variety of applications, including basic research, therapies for inborn genetic defects, cancer, AIDS, tissue engineering1,2, and vaccination3. Most available systems have s...

    Dirk Esser, Hiroshi Amanuma, Atsushi Yoshiki, Moriaki Kusakabe… in Nature Biotechnology (2000)

  2. Article

    Open Access

    Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation

    CRISPR-Cas9 gene-editing technology has facilitated the generation of knockout mice, providing an alternative to cumbersome and time-consuming traditional embryonic stem cell-based methods. An earlier study re...

    Channabasavaiah B. Gurumurthy, Aidan R. O’Brien, Rolen M. Quadros… in Genome Biology (2019)

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  3. Article

    Open Access

    Response to correspondence on “Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation”

    Channabasavaiah B. Gurumurthy, Aidan R. O’Brien, Rolen M. Quadros… in Genome Biology (2021)

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