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  1. Article

    Open Access

    Reducing the risk of impaired bone apposition to titanium screws with the use of fibroblast growth factor-2−apatite composite layer coating

    Loosening of screws is a common problem in orthopedic and maxillofacial surgery. Modifying the implant surface to improve the mechanical strength of screws has been tried and reported. We developed screws coat...

    Kengo Fujii, Atsuo Ito, Hirotaka Mutsuzaki… in Journal of Orthopaedic Surgery and Research (2017)

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  2. No Access

    Article

    Enhanced wound healing associated with Sharpey’s fiber-like tissue formation around FGF-2-apatite composite layers on percutaneous titanium screws in rabbits

    Pin-tract infections are the most common complications of external fixation. To solve the problem, we developed a fibroblast growth factor-2 (FGF-2)-apatite composite layer for coating titanium screws. The pur...

    Hirotaka Mutsuzaki, Atsuo Ito, Yu Sogo… in Archives of Orthopaedic and Trauma Surgery (2012)