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Article
Open AccessPlasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer’s disease
Staging amyloid-beta (Aβ) pathophysiology according to the intensity of neurodegeneration could identify individuals at risk for cognitive decline in Alzheimer’s disease (AD). In blood, phosphorylated tau (p-t...
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Article
Open AccessDynamic contrast-enhanced MRI shows altered blood–brain barrier function of deep gray matter structures in neuroborreliosis: a case–control study
Main aim was assessment of regional blood–brain barrier (BBB) function by dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in patients with neuroborreliosis. Secondary aim was to study the correl...
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Article
Open AccessA densely interconnected network for deep learning accelerated MRI
To improve accelerated MRI reconstruction through a densely connected cascading deep learning reconstruction framework.
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Article
Correction to: Automated segmentation of magnetic resonance bone marrow signal: a feasibility study
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Article
Open AccessAutomated segmentation of magnetic resonance bone marrow signal: a feasibility study
Manual assessment of bone marrow signal is time-consuming and requires meticulous standardisation to secure adequate precision of findings.
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Article
Open AccessEvidence for widespread alterations in cortical microstructure after 32 h of sleep deprivation
Cortical microstructure is influenced by circadian rhythm and sleep deprivation, yet the precise underpinnings of these effects remain unclear. The ratio between T1-weighted and T2-weighted magnetic resonance ima...
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Article
Open AccessOperator dependency of arterial input function in dynamic contrast-enhanced MRI
To investigate the effect of inter-operator variability in arterial input function (AIF) definition on kinetic parameter estimates (KPEs) from dynamic contrast-enhanced (DCE) MRI in patients with high-grade gl...
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Article
Open AccessAuthor Correction: The Impact of MRI Features and Observer Confidence on the Treatment Decision-Making for Patients with Untreated Glioma
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Article
Determination of oxygen r1 at 3 Tesla using samples with a concentration range of dissolved oxygen
To investigate the sensitivity of modified Look–Locker inversion recovery (MOLLI) to measure changes in dissolved oxygen (DO) concentrations in water samples and to calculate sequence-specific relaxivity (r1m) an...
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Chapter
MRI Perfusion Techniques
MRI-based perfusion techniques have become an integral part of neuroimaging and several different MRI techniques are now available for analysis of tissue perfusion and related hemodynamic parameters. This chap...
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Article
Open AccessThe Impact of MRI Features and Observer Confidence on the Treatment Decision-Making for Patients with Untreated Glioma
In a blind, dual-center, multi-observer setting, we here identify the pre-treatment radiologic features by Magnetic Resonance Imaging (MRI) associated with subsequent treatment options in patients with glioma....
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Article
Permeability measurement using dynamic susceptibility contrast magnetic resonance imaging enhances differential diagnosis of primary central nervous system lymphoma from glioblastoma
To test if adding permeability measurement to perfusion obtained from dynamic susceptibility contrast MRI (DSC-MRI) improves diagnostic performance in the differentiation of primary central nervous system lymp...
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Article
Precision of T1-relaxation time measurements in the hepatic portal vein: influence of measurement technique and sequence parameters
To investigate the effects of a range of parameter settings on T1 measurement stability in the portal vein using the T1-map** sequences Look-Locker (LL) and Modified Look-Locker inversion recovery (MOLLI).
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Article
Magnetic resonance imaging perfusion is associated with disease severity and activity in multiple sclerosis
The utility of perfusion-weighted imaging in multiple sclerosis (MS) is not well investigated. The purpose of this study was to compare baseline normalized perfusion measures in subgroups of newly diagnosed MS...
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Article
Erratum to: Optimal differentiation of high- and low-grade glioma and metastasis: a meta-analysis of perfusion, diffusion, and spectroscopy metrics
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Article
Optimal differentiation of high- and low-grade glioma and metastasis: a meta-analysis of perfusion, diffusion, and spectroscopy metrics
To perform a meta-analysis of advanced magnetic resonance imaging (MRI) metrics, including relative cerebral blood volume (rCBV), normalized apparent diffusion coefficient (nADC), and spectroscopy ratios choli...
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Article
Open AccessHippocampal subfield atrophy in relation to cerebrospinal fluid biomarkers and cognition in early Parkinson’s disease: a cross-sectional study
Cognition is often affected early in Parkinson’s disease (PD). Lewy body and amyloid β (Aβ) pathology and cortical atrophy may be involved. The aim of this study was to examine whether medial temporal lobe str...
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Article
Influence of blood/tissue differences in contrast agent relaxivity on tracer-based MR perfusion measurements
Perfusion assessment by monitoring the transport of a tracer bolus depends critically on conversion of signal intensity into tracer concentration. Two main assumptions are generally applied for this conversio...
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Chapter and Conference Paper
Towards an Integrated Semantic Framework for Neurological Multidimensional Data Analysis
Medical institutions are increasingly aware of the vast amount of available data they have and its potential benefits. These data are being analyzed and shared at institutions all around the world, however, th...
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Article
Hepatic cellular distribution and degradation of iron oxide nanoparticles following single intravenous injection in rats: implications for magnetic resonance imaging
The purpose of this study was to determine the cellular distribution and degradation in rat liver following intravenous injection of superparamagnetic iron oxide nanoparticles used for magnetic resonance imagi...
