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Amyloid-beta and tau pathologies act synergistically to induce novel disease stage-specific microglia subtypes

Amongst risk alleles associated with late-onset Alzheimer’s disease (AD), those that converged on the regulation of microglia activity have emerged as central to disease progression. Yet, how canonical amyloid...

Dong Won Kim, Kevin J. Tu, Alice Wei, Ashley J. Lau… in Molecular Neurodegeneration (2022)