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    Article

    Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL

    During the progression of atherosclerosis, autoantibodies are induced to epitopes of oxidized low-density lipoprotein (oxLDL) and active immunization of hypercholesterolemic mice with oxLDL ameliorates atherog...

    Christoph J Binder, Sohvi Hörkkö, Asheesh Dewan, Mi-Kyung Chang in Nature Medicine (2003)

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    Innate and acquired immunity in atherogenesis

    Traditional risk factors like hypercholesterolemia are important for atherogenesis, but it is now apparent that the immune system also plays an important role. Uncovering the mechanisms by which specific compo...

    Christoph J. Binder, Mi-Kyung Chang, Peter X. Shaw, Yury I. Miller in Nature Medicine (2002)