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  1. Article

    Open Access

    Intravital electrochemical nanosensor as a tool for the measurement of reactive oxygen/nitrogen species in liver diseases

    Reactive oxygen/nitrogen species (ROS/RNS) are formed during normal cellular metabolism and contribute to its regulation, while many pathological processes are associated with ROS/RNS imbalances. Modern method...

    Tatiana Abakumova, Alexander Vaneev, Victor Naumenko… in Journal of Nanobiotechnology (2022)

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    Article

    A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells

    The variability in the prognosis of individuals with hepatocellular carcinoma (HCC) suggests that HCC may comprise several distinct biological phenotypes. These phenotypes may result from activation of differe...

    Ju-Seog Lee, Jeonghoon Heo, Louis Libbrecht, In-Sun Chu… in Nature Medicine (2006)

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    Article

    Application of comparative functional genomics to identify best-fit mouse models to study human cancer

    Genetically modified mice have been extensively used for analyzing the molecular events that occur during tumor development. In many, if not all, cases, however, it is uncertain to what extent the mouse models...

    Ju-Seog Lee, In-Sun Chu, Arsen Mikaelyan, Diego F Calvisi, Jeonghoon Heo… in Nature Genetics (2004)