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Article
Open AccessExposure to 16 h of normobaric hypoxia induces ionic edema in the healthy brain
Following prolonged exposure to hypoxic conditions, for example, due to ascent to high altitude, stroke, or traumatic brain injury, cerebral edema can develop. The exact nature and genesis of hypoxia-induced e...
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Article
Open AccessSodium MRI in Multiple Sclerosis is Compatible with Intracellular Sodium Accumulation and Inflammation-Induced Hyper-Cellularity of Acute Brain Lesions
The cascade of inflammatory pathogenetic mechanisms in multiple sclerosis (MS) has no specific conventional MRI correlates. Clinicians therefore stipulate improved imaging specificity to define the pathologica...
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Article
Open AccessVirtual Raters for Reproducible and Objective Assessments in Radiology
Volumetric measurements in radiologic images are important for monitoring tumor growth and treatment response. To make these more reproducible and objective we introduce the concept of virtual raters (VRs). A ...
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Chapter and Conference Paper
Crutchfield Information Metric: A Valid Tool for Quality Control of Multiparametric MRI Data?
We propose an information theoretic framework to automatically infer the physical relationship and asses the quality of multiparametric MRI sequences. The method is based on the Crutchfield information metric....