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Article
Combined IgG4κ and IgG1λ deposition in the glomerular and tubular basement membrane accompanied by autoimmune neutropenia (AIN) and immune thrombocytopenia (ITP)
A 48-year-old male was admitted to our hospital with nephrotic syndrome. Light-microscopic examination of a renal biopsy specimen showed almost normal glomerular appearance, however, immunofluorescence examina...
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Article
High uric acid level is a risk factor for progression of IgA nephropathy with chronic kidney disease stage G3a
High uric acid level is a known risk factor for deterioration of renal function in chronic kidney disease (CKD), but its influence on the progression of IgA nephropathy (IgAN) remains unclear.
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Article
Positive C1q staining associated with poor renal outcome in membranoproliferative glomerulonephritis
Pathogenesis and clinical prognosis of membranoproliferative glomerulonephritis (MPGN) has not yet been established.
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Article
Long-term damage assessment in patients with microscopic polyangiitis and renal-limited vasculitis using the Vasculitis Damage Index
The Vasculitis Damage Index (VDI) is used to define the degree of damage occurring in patients with systemic vasculitis. We conducted a retrospective study of 30 patients with microscopic polyangiitis (MPA) an...
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Article
Long-term beneficial effects of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker therapy for patients with advanced immunoglobulin A nephropathy and impaired renal function
There are few reports analyzing the effects of angiotensin-converting enzyme inhibitors (ACEIs) and/or angiotensin receptor blockers (ARBs) on the long-term renal survival of advanced immunoglobulin A nephropa...
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Article
Low-Dose Losartan Therapy Reduces Proteinuria in Normotensive Patients with Immunoglobulin A Nephropathy
The present study was designed to assess the antiproteinuric effects of a low dose of an angiotensin II–receptor blocker, losartan, in normotensive patients with immunoglobulin A (IgA) nephropathy. We performe...