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    Article

    Spectroscopic investigations on the interactions of potent platinum(II) anticancer agents with bovine serum albumin

    The interactions of three platinum(II)-based anticancer complexes [(5,6-dimethyl-1,10-phenanthroline)(1S,2S-diaminocyclohexane)platinum(II)]2+, [(5,6-dimethyl-1,10-phenanthroline)(1R,2R-diaminocyclohexane)platinu...

    Anwen M. Krause-Heuer, William S. Price… in Journal of Chemical Biology (2012)

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    Chapter

    The Synthesis of Platinum(II) Intercalators

    The pharmacological properties of any drug are largely dependent on binding interactions with biomolecules. The investigation of such interactions is essential to gain some understanding of the mechanisms of d...

    Anwen M. Krause-Heuer, Madhura Manohar… in Metallointercalators (2011)

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    Chapter

    Pulsed Gradient Spin-Echo NMR

    Translational diffusion (also referred to as self-diffusion, Brownian motion, or random walks) plays a vital role in all sorts of molecular dynamics in biological systems (e.g., ligand–DNA interactions, lipid–...

    Gang Zheng, Anwen M. Krause-Heuer, William S. Price in Metallointercalators (2011)