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Article
Open AccessThe impact of IGF-I, puberty and obesity on early retinopathy in children: a cross-sectional study
Childhood obesity has been correlated with coronary heart disease, but the correlation with microvascular disease remains unclear. The retinal microcirculation is affected early in the process of atheroscleros...
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Article
Open AccessAdvantages of a next generation sequencing targeted approach for the molecular diagnosis of retinoblastoma
Retinoblastoma (RB) is the most common malignant childhood tumor of the eye and results from inactivation of both alleles of the RB1 gene. Nowadays RB genetic diagnosis requires classical chromosome investigation...
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Article
Open AccessCongenital cystic eye associated with a low-grade cerebellar lesion that spontaneously regressed
Congenital cystic eye is an exceedingly rare ocular malformative disease, originated from the failure in the invagination of the optic vesicle during the fetal period and it can be associated with other ocular...