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Chapter
Additives: Preservatives, Antioxidants, Dyes, and Others
An excipient—also called additive—is an inert substance added to a drug to change dissolution or the kinetics of absorption, improve stability, influence palatability, or create a distinctive appearance. Prese...
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Chapter
Skin Tests
Skin tests are crucial to detect sensitization in drug hypersensitivity. Three skin tests, patch test, skin prick test (SPT), and intradermal test (IDT), are used for the etiological diagnosis of an adverse re...
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Article
Systemic sclerosis is associated with lower limb vascular stiffness and microvascular impairment: results from a prospective study
Systemic sclerosis (SSc) is a connective tissue disease characterized by microangiopathy. Peripheral arterial disease, increasingly studied during SSc, is responsible for digital ulcers, associated with a high...
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Article
Open AccessA new phototherapy regimen during winter as an add-on therapy, coupled with oral vitamin D supplementation, for the long-term control of atopic dermatitis: study protocol for a multicentre, randomized, crossover, pragmatic trial – the PRADA trial
Atopic dermatitis is a highly prevalent, chronic, relapsing disease in both adults and children. On the severity spectrum, lower-end patients benefit from small amounts of topical anti-inflammatory treatments ...
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Chapter
In Vitro and In Vivo Tests in Cutaneous Adverse Drug Reactions
Done with a good practice detailed in this paper, drug skin tests are useful for the diagnosis of drug hypersensitivities (HS). Drug patch tests can be done in all cutaneous adverse drug reactions but anaphyla...
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Article
Open AccessEpidermal necrolysis French national diagnosis and care protocol (PNDS; protocole national de diagnostic et de soins)
Epidermal necrolysis (EN) encompasses Stevens-Johnson syndrome (SJS, < 10% of the skin affected), Lyell syndrome (toxic epidermal necrolysis, TEN, with ≥30% of the skin affected) and an overlap syndrome (10 to...
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Article
Pseudoxanthoma elasticum and coeliac disease: a fortuitous association?
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Article
Open Access7th Drug hypersensitivity meeting: part two
Poster walk 11: miscellaneous drug hypersensitivity 2 (P92–P94, P96–P101)
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Article
Development of monoclonal gammopathy under biotherapy in psoriasis: a French multicenter retrospective study
Biotherapies or targeted therapies are fairly new treatments indicated for moderate to severe psoriasis. The side effects appear to be mainly infectious or cancerous. The role of biotherapies in the developmen...
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Article
Occupational protein contact dermatitis
Occupational contact dermatitis is generally caused by haptens but can also be induced by proteins causing mainly immunological contact urticaria (ICU); chronic hand eczema in the context of protein contact de...
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Article
Good efficacy and tolerability of ustekinumab in a patient with severe psoriasis under haemodialysis
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Article
Open AccessAnalysis of cross-reactivity between radio -contrast media in 97 hypersensitivity reactions
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Article
Open AccessNonirritant concentrations and amount of active ingredient in drug patch tests optimal concentrations for DPTs
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Article
Open AccessDNA copy number variations in drug reaction with eosinophilia and systemic symptoms (DRESS) identifying 2 new candidates genes
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Article
Open AccessAn immunohistochemical study of the granulysin expression of 6 types of proven adverse cutaneous drug reaction
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Article
Skin Testing and Patch Testing in Non-IgE-Mediated Drug Allergy
Drug skin tests can reproduce delayed hypersensitivity to drugs and entail a moderate reexposure of patients to offending drugs. Drug patch tests (DPTs) and prick tests can be done with any commercialized form...
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Article
The use of three-dimensional similarity in assessing the risk of cross-reactivity between carbamazepine and psychotropic drugs
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Article
The European Standard Series and its additions: are they of any use in 2013?
This study has two purposes: — to know whether the European standard series is still the key reference when it comes to contact dermatitis, i.e., are its components still the most frequently involved allergens...
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Article
Fluindione and drug reaction with eosinophilia and systemic symptoms: an unrecognised adverse effect?
Fluindione is an oral vitamin K antagonist (indanedione derivative) exclusively marketed in France and Luxembourg, known to have immuno-allergic adverse effects such as hepatitis, fever or interstitial nephrit...
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Article
Open AccessAssociations of airway inflammation and responsiveness markers in non asthmatic subjects at start of apprenticeship
Bronchial Hyperresponsiveness (BHR) is considered a hallmark of asthma. Other methods are helpful in epidemiological respiratory health studies including Fractional Exhaled Nitric Oxide (FENO) and Eosinophils ...
