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  1. Article

    Open Access

    Organisational implementation climate in implementing internet-based cognitive behaviour therapy for depression

    Internet-based Cognitive Behaviour Therapy (iCBT) for depression have been implemented in routine care across Europe in varying ways, at various scales and with varying success. This study aimed to advance our...

    Christiaan Vis, Annet Kleiboer, Mayke Mol in BMC Health Services Research (2022)

  2. Article

    Online therapy: an added value for inpatient routine care? Perspectives from mental health care professionals

    Internet-delivered interventions can be effective in treating mental disorders. However, their rate of use in German psychiatric inpatient routine care is low. The current study aimed to investigate the attitu...

    Julia Sander, Felix Bolinski in European Archives of Psychiatry and Clinic… (2022)

  3. No Access

    Chapter and Conference Paper

    pH-RL: A Personalization Architecture to Bring Reinforcement Learning to Health Practice

    While reinforcement learning (RL) has proven to be the approach of choice for tackling many complex problems, it remains challenging to develop and deploy RL agents in real-life scenarios successfully. This pa...

    Ali el Hassouni, Mark Hoogendoorn in Machine Learning, Optimization, and Data S… (2022)

  4. Article

    Open Access

    Tailored implementation of internet-based cognitive behavioural therapy in the multinational context of the ImpleMentAll project: a study protocol for a stepped wedge cluster randomized trial

    Internet-based Cognitive Behavioural Therapy (iCBT) is found effective in treating common mental disorders. However, the use of these interventions in routine care is limited. The international ImpleMentAll st...

    Leah Bührmann, Josien Schuurmans, Jeroen Ruwaard, Margot Fleuren in Trials (2020)

  5. Article

    Open Access

    Improving adherence to an online intervention for low mood with a virtual coach: study protocol of a pilot randomized controlled trial

    Internet-based cognitive-behavioral therapy (iCBT) is more effective when it is guided by human support than when it is unguided. This may be attributable to higher adherence rates that result from a positive ...

    Simon Provoost, Annet Kleiboer, José Ornelas, Tibor Bosse, Jeroen Ruwaard in Trials (2020)

  6. Article

    Open Access

    Efficacy and cost-effectiveness of a blended cognitive behavioral therapy for depression in Spanish primary health care: study protocol for a randomised non-inferiority trial

    Data from primary health care in Spain show a high prevalence of the major depressive disorder. Blended treatment (combination of face-to-face and online components) seems to be a very promising tool for the o...

    Mª Dolores Vara, Rocío Herrero, Ernestina Etchemendy, Macarena Espinoza in BMC Psychiatry (2018)

  7. Article

    Open Access

    Effectiveness of a transdiagnostic individually tailored Internet-based and mobile-supported intervention for the indicated prevention of depression and anxiety (ICare Prevent) in Dutch college students: study protocol for a randomised controlled trial

    Depression and anxiety are common and co-morbid disorders that affect a significant proportion of students. Innovative prevention strategies targeting both conditions are needed to reduce their health burden a...

    Felix Bolinski, Annet Kleiboer, Eirini Karyotaki, Judith E. Bosmans in Trials (2018)

  8. Article

    Open Access

    European COMPARative Effectiveness research on blended Depression treatment versus treatment-as-usual (E-COMPARED): study protocol for a randomized controlled, non-inferiority trial in eight European countries

    Effective, accessible, and affordable depression treatment is of high importance considering the large personal and economic burden of depression. Internet-based treatment is considered a promising clinical an...

    Annet Kleiboer, Jan Smit, Judith Bosmans, Jeroen Ruwaard, Gerhard Andersson in Trials (2016)

  9. Article

    Open Access

    Determinants of help-seeking behavior in depression: a cross-sectional study

    Although evidence-based and effective treatments are available for people with depression, a substantial number does not seek or receive help. Therefore, it is important to gain a better understanding of the r...

    Anke M. Boerema, Annet Kleiboer, Aartjan T. F. Beekman, Kim van Zoonen in BMC Psychiatry (2016)

  10. No Access

    Article

    Monitoring symptoms at home: what methods would cancer patients be comfortable using?

    This study aimed to determine which methods of remote symptom assessment cancer outpatients would be comfortable using, including those involving information technology, and whether this varied with age and ge...

    Annet Kleiboer, Katie Gowing, Christian Holm Hansen in Quality of Life Research (2010)