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Open AccessThe role of miR-200b/c in balancing EMT and proliferation revealed by an activity reporter
Since their discovery, microRNAs (miRNAs) have been widely studied in almost every aspect of biology and medicine, leading to the identification of important gene regulation circuits and cellular mechanisms. H...
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Article
Open AccessThymidylate synthase maintains the de-differentiated state of triple negative breast cancers
Cancer cells frequently boost nucleotide metabolism (NM) to support their increased proliferation, but the consequences of elevated NM on tumor de-differentiation are mostly unexplored. Here, we identified a r...