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    Perturbation of CD4+ and CD8+ T-cell repertoires during progression to AIDS and regulation of the CD4+ repertoire during antiviral therapy

    The T-cell antigen receptor (TCR) repertoire was studied longitudinally by analyzing the varying lengths of the beta chain CDR3 hypervariable region during the course of HIV-1 infection and following combinati...

    Guy Gorochov, Avidan U. Neumann, Anne Kereveur, Christophe Parizot… in Nature Medicine (1998)