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  1. Article

    Open Access

    Vitamin D upregulates the macrophage complement receptor immunoglobulin in innate immunity to microbial pathogens

    Vitamin D deficiency remains a global concern. This ‘sunshine’ vitamin is converted through a multistep process to active 1,25-dihydroxyvitamin D3 (1,25D), the final step of which can occur in macrophages. Here w...

    Annabelle G. Small, Sarah Harvey, Jaspreet Kaur, Trishni Putty… in Communications Biology (2021)

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  2. Article

    Open Access

    Cytokines regulate complement receptor immunoglobulin expression and phagocytosis of Candida albicans in human macrophages: A control point in anti-microbial immunity

    Complement Receptor Immunoglobulin (CRIg), selectively expressed by macrophages, plays an important role in innate immunity by promoting phagocytosis of bacteria. Thus modulation of CRIg on macrophages by cyto...

    Usma Munawara, Annabelle G. Small, Alex Quach, Nick N. Gorgani… in Scientific Reports (2017)

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