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Article
Kinesin Light Chain 1 Gene Haplotypes in Three Conformational Diseases
A functional intracellular transport system is essential to maintain cell shape and function especially in elongated cells, e.g. neurons and lens fibre cells. Impaired intracellular transport has been suggeste...
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Article
Open AccessAssociation of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease
Oxidative stress is heavily implicated in the pathogenic process of Parkinson's disease. Varying capacity to detoxify radical oxygen species through induction of phase II antioxidant enzymes in substantia nigr...
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Article
Do polymorphisms in transcription factors LMX1A and LMX1B influence the risk for Parkinson’s disease?
The key symptoms of Parkinson’s disease (PD) are caused by degeneration of dopamine neurons originating in substantia nigra. Whereas, transcription factor LMX1A is crucial for the differentiation of mesencepha...