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  1. Article

    The UGT2A1/UGT2A2 locus is associated with COVID-19-related loss of smell or taste

    Using online surveys, we collected data regarding COVID-19-related loss of smell or taste from 69,841 individuals. We performed a multi-ancestry genome-wide association study and identified a genome-wide signi...

    Janie F. Shelton, Anjali J. Shastri, Kipper Fletez-Brant… in Nature Genetics (2022)

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  2. Article

    Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity

    COVID-19 presents with a wide range of severity, from asymptomatic in some individuals to fatal in others. Based on a study of 1,051,032 23andMe research participants, we report genetic and nongenetic associat...

    Janie F. Shelton, Anjali J. Shastri, Chelsea Ye, Catherine H. Weldon… in Nature Genetics (2021)

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    Article

    Immunodominant, protective response to the parasite Toxoplasma gondii requires antigen processing in the endoplasmic reticulum

    The Toxoplasma gondii peptides recognized by protective CD8+ T cells remain uncharacterized. Shastri and colleagues identify an immunodominant T. gondii peptide generated by a mechanism dependent on the endoplasm...

    Nicolas Blanchard, Federico Gonzalez, Marie Schaeffer… in Nature Immunology (2008)