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Article
Endokrine Orbitopathie als Ursache einer Diplopie im Senium – Unterschiede zwischen Jung und Alt
Die endokrine Orbitopathie (EO) ist eine Autoimmunerkrankung, meist mit einer Schilddrüsenerkrankung assoziiert, die zu Entzündungen, Adipogenese und Fibrose führt. Die Schwere der EO kann zwischen Individuen ...
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Article
Open AccessMR Imaging Characteristics of Solitary Fibrous Tumors of the Orbit
Solitary fibrous tumor (SFT) of the orbit is a rare tumor that was first described in 1994. We aimed to investigate its imaging characteristics that may facilitate the differential diagnosis between SFT and ot...
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Article
Open AccessMRI-based long-term follow-up of indolent orbital lymphomas after curative radiotherapy: imaging remission criteria and volumetric regression kinetics
We systematically analyzed the kinetics of tumor regression, the impact of residual lesions on disease control and the applicability of the Lugano classification in follow-up MRI of orbital non-Hodgkin lymphom...
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Article
Open AccessProposing a surgical algorithm for graduated orbital decompression in patients with Graves’ orbitopathy
To determine the outcome after orbital decompression using a graduated technique, adapting the surgical technique according to individual patients’ disease characteristics.
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Article
Open Access18 F-FDG-PET/MRI in patients with Graves’ orbitopathy.
Currently, therapeutic management of patients with Graves’ orbitopathy (GO) relies on clinical assessments and MRI. However, monitoring of inflammation remains difficult since external inflammatory signs do no...
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Article
Open AccessModulating gut microbiota in a mouse model of Graves’ orbitopathy and its impact on induced disease
Graves’ disease (GD) is an autoimmune condition in which autoantibodies to the thyrotropin receptor (TSHR) cause hyperthyroidism. About 50% of GD patients also have Graves’ orbitopathy (GO), an intractable dis...
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Article
Open AccessOrbital aspergillosis: a case report and review of the literature
Orbital aspergillosis is a rare sight- and life-threatening fungal infection affecting immunocompromised or otherwise healthy patients. It is often misdiagnosed due to its unspecific clinical and radiologic ap...
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Chapter
Endokrine Orbitopathie (EO) (engl. Graves’ Orbitopathy [GO], Thyroid Eye Disease [TED])
ICD-10-Code H06.2 Exophthalmus bei Funktionsstörung der Schilddrüsen
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Article
Open AccessVisual rehabilitation of patients with corneal diseases
Although most patients with visual impairment due to corneal diseases can be treated successfully with surgery, some require visual rehabilitation to restore reading ability. To evaluate the best LVAs especial...
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Article
The influence of orbital decompression on objective nasal function in patients with graves’ orbitopathy
To determine the influence of anatomical changes after orbital decompression to nasal function.
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Article
Open AccessGraves’ orbitopathy occurs sex-independently in an autoimmune hyperthyroid mouse model
Graves’ orbitopathy (GO) is the most common extra thyroidal complication of Graves’ disease (GD) and occurs predominantly in women but more severe in men. The reason for this effect of gender on GO is unknown....
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Article
Open AccessCombining micro-RNA and protein sequencing to detect robust biomarkers for Graves’ disease and orbitopathy
Graves’ Disease (GD) is an autoimmune condition in which thyroid-stimulating antibodies (TRAB) mimic thyroid-stimulating hormone function causing hyperthyroidism. 5% of GD patients develop inflammatory Graves’...
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Article
Open AccessGut microbiota in experimental murine model of Graves’ orbitopathy established in different environments may modulate clinical presentation of disease
Variation in induced models of autoimmunity has been attributed to the housing environment and its effect on the gut microbiota. In Graves’ disease (GD), autoantibodies to the thyrotropin receptor (TSHR) cause...
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Article
Outcome of a graduated minimally invasive facial reanimation in patients with facial paralysis
Peripheral paralysis of the facial nerve is the most frequent of all cranial nerve disorders. Despite advances in facial surgery, the functional and aesthetic reconstruction of a paralyzed face remains a chall...
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Chapter
An Animal Model of Graves’ Orbitopathy
Graves’ orbitopathy (GO) is an inflammatory orbital disease that frequently arises as a consequence of Graves’ disease, a common autoimmune thyroid condition. The thyrotropin stimulating hormone receptor (TSHR...
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Article
Superior oblique tucking with versus without additional inferior oblique recession for acquired trochlear nerve palsy
Inferior oblique recession (IOR), superior oblique tucking or advancement (SOT) and a combination of both (SOT&IOR) are most popular as treatments for acquired trochlear nerve (N.IV) palsy. Recently, it has be...
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Chapter
Modern Treatment Concepts in Graves Disease
Graves orbitopathy (GO) is part of an autoimmune systemic disease, which is composed of hyperthyroidism, orbitopathy, dermopathy, and acropachy
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Article
Bedeutung der TSH-Rezeptor-Antikörper für die Diagnose des Morbus Basedow sowie die Prognoseabschätzung der Schilddrüsenüberfunktion und der endokrinen Orbitopathie
Die Autoimmunhyperthyreose (Synonym Morbus Basedow) ist eine antikörpervermittelte Autoimmunerkrankung, bei der es zu einer Stimulation der Schilddrüse, aber auch anderer Zielgewebe kommt. Neben der Hyperthyre...
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Chapter
Human Recombinant Interferon-α2a (rhIFNα2a) for the Treatment of Behçet’s Disease with Sight-Threatening Retinal Vasculitis
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Article
Prognostic value of the pattern electroretinogram in cases of tumors affecting the optic pathway
· Background: Tumors compressing the optic pathway may lead to irreversible loss of vision which may be detected by the pattern electroretinogram (PERG) because of its relation to ganglion cell function. · Met...
