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  1. Article

    Open Access

    Patient-specific primary and pluripotent stem cell-derived stromal cells recapitulate key aspects of arrhythmogenic cardiomyopathy

    Primary cardiac mesenchymal stromal cells (C-MSCs) can promote the aberrant remodeling of cardiac tissue that characterizes arrhythmogenic cardiomyopathy (ACM) by differentiating into adipocytes and myofibrobl...

    Angela Serena Maione, Viviana Meraviglia, Lara Iengo, Martina Rabino… in Scientific Reports (2023)

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  2. Article

    Open Access

    Impaired Plakophilin-2 in obesity breaks cell cycle dynamics to breed adipocyte senescence

    Plakophilin-2 (PKP2) is a key component of desmosomes, which, when defective, is known to promote the fibro-fatty infiltration of heart muscle. Less attention has been given to its role in adipose tissue. We r...

    Aina Lluch, Jessica Latorre, Angela Serena-Maione, Isabel Espadas… in Nature Communications (2023)

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