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  1. Article

    Open Access

    Efficacy and safety of linagliptin in type 2 diabetes subjects at high risk for renal and cardiovascular disease: a pooled analysis of six phase III clinical trials

    In patients with type 2 diabetes mellitus (T2DM), hypertension and microalbuminuria are predictive markers for increased renal and cardiovascular risk. This post hoc analysis of data from a global development pro...

    Maximilian von Eynatten, Yan Gong, Angela Emser… in Cardiovascular Diabetology (2013)

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  2. No Access

    Article

    Outcome of 11 children with ependymoblastoma treated within the prospective HIT-trials between 1991 and 2006

    Ependymoblastoma is a rare malignant brain tumor of early childhood. Data on clinical behavior and optimal treatment strategies are scarce. We report on 11 consecutively treated children with centrally confirm...

    Nicolas U. Gerber, Katja von Hoff, André O. von Bueren… in Journal of Neuro-Oncology (2011)

  3. No Access

    Article

    Natural history and management of low-grade glioma in NF-1 children

    Pediatric neurofibromatosis type 1 (NF-1) patients are prone to develo** low-grade glioma (LGG). The HIT-LGG study 1996 aimed to observe the natural history of pediatric LGG and to postpone irradiation in yo...

    Pablo Hernáiz Driever, Stephan von Hornstein, Torsten Pietsch… in Journal of Neuro-Oncology (2010)

  4. No Access

    Article

    Treatment options in childhood pontine gliomas

    Pontine gliomas are the subgroup of brainstem gliomas with the worst prognosis. Controversial treatment approaches are discussed.

    Sabine Wagner, Monika Warmuth-Metz, Angela Emser… in Journal of Neuro-Oncology (2006)

  5. No Access

    Article

    Melatonin Treatment in Obese Patients with Childhood Craniopharyngioma and Increased Daytime Sleepiness

    Craniopharyngioma is a rare dysontogenetic benign tumor. Patients frequently suffer from endocrine deficiencies, sleep disturbances and obesity due to pituitary and hypothalamic lesions. A self-assessment dayt...

    Hermann L. Müller, Georg Handwerker, Ursel Gebhardt… in Cancer Causes & Control (2006)

  6. No Access

    Article

    Longitudinal study on quality of life in 102 survivors of childhood craniopharyngioma

    We longitudinally analysed functional capacity and quality of life (QoL) in 102 patients with a childhood craniopharyngioma during follow-up.

    Hermann L. Müller, Gina Bruhnken, Angela Emser, Andreas Faldum… in Child's Nervous System (2005)

  7. No Access

    Article

    Functional capacity and body mass index in patients with sellar masses—cross-sectional study on 403 patients diagnosed during childhood and adolescence

    We analyzed the impact of tumour localization and histology on functional capacity (FC) and body mass index (BMI) in children with sellar masses.

    Hermann L. Müller, Ursel Gebhardt, Andreas Faldum, Angela Emser… in Child's Nervous System (2005)