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Article
Advance care planning in multiple system atrophy: ethical challenges and considerations
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Article
Open AccessFactors associated with self-rated health in people with late-stage parkinson’s and cognitive impairment
To investigate the contributors to self-rated health in people with late-stage Parkinson’s disease (PD) and cognitive impairment.
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Article
Open AccessPredictors of short-term anxiety outcome in subthalamic stimulation for Parkinson’s disease
The effects of subthalamic nucleus deep brain stimulation (STN-DBS) on anxiety in Parkinson’s disease (PD) are understudied. We identified clinical predictors of STN-DBS effects on anxiety in this study. In th...
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Open AccessMeaning in Life in Late-Stage Parkinson’s Disease: Results from the Care of Late-Stage Parkinsonism Study (CLaSP) in Six European Countries
The Care of Late-Stage Parkinsonism (CLaSP) study is a longitudinal, multicentre, prospective cohort study to assess the needs and provision of care for people with late-stage Parkinson’s disease and their car...
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Open AccessIntervention components in the self-management of Parkinson’s: a mixed-methods synthesis of qualitative and quantitative evidence
Self-management interventions consist of multiple components to support people in the management of medical, emotional, and behavioural aspects of their condition, and aim to improve quality of life, function,...
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Open AccessClinical and cost-effectiveness of ‘Live Well with Parkinson’s’ self-management intervention versus treatment as usual for improving quality of life for people with Parkinson’s: study protocol for a randomised controlled trial
The Live Well with Parkinson’s Self-Management Toolkit is designed for use in the NHS to support people with Parkinson’s, their carers and health professionals in managing motor and non-motor symptoms and prom...
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Article
Open AccessThe experience of Anxiety for people with Parkinson’s disease
Anxiety is a common non-motor symptom of Parkinson’s disease (PD) associated with increased disability and reduced quality of life. However, anxiety is poorly understood, underdiagnosed, and undertreated. To d...
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Article
Open AccessPolygenic risk score-based phenome-wide association study identifies novel associations for Tourette syndrome
Tourette Syndrome (TS) is a complex neurodevelopmental disorder characterized by vocal and motor tics lasting more than a year. It is highly polygenic in nature with both rare and common previously associated ...
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Article
Open AccessVitamin D levels in children and adolescents with chronic tic disorders: a multicentre study
This study investigated whether vitamin D is associated with the presence or severity of chronic tic disorders and their psychiatric comorbidities. This cross-sectional study compared serum 25-hydroxyvitamin D...
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Article
Open AccessThe Cost Effectiveness of Levodopa-Carbidopa Intestinal Gel in the Treatment of Advanced Parkinson’s Disease in England
Parkinson’s disease is a progressive neurodegenerative disease, which significantly impacts patients’ quality of life and is associated with high treatment and direct healthcare costs. In England, levodopa/car...
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Open AccessChange in the incidence of Parkinson’s disease in a large UK primary care database
Parkinson’s disease (PD) has the fastest rising prevalence of all neurodegenerative diseases worldwide. However, it is unclear whether its incidence has increased after accounting for age and changes in diagno...
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Article
Open AccessSystematic review and meta-analysis of clinical effectiveness of self-management interventions in Parkinson’s disease
Parkinson’s disease is a complex neurodegenerative condition with significant impact on quality of life (QoL), wellbeing and function. The objective of this review is to evaluate the clinical effectiveness of ...
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Article
Open AccessDevelo** and assessing a new web-based tap** test for measuring distal movement in Parkinson’s disease: a Distal Finger Tap** test
Disability in Parkinson’s disease (PD) is measured by standardised scales including the MDS-UPDRS, which are subject to high inter and intra-rater variability and fail to capture subtle motor impairment. The B...
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Open AccessHealth care professionals’ perspectives on self-management for people with Parkinson’s: qualitative findings from a UK study
Parkinson’s disease is a long-term, complex health condition. To improve or maintain quality of life, people with Parkinson’s can have an active involvement in their care through self-management techniques. Gi...
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Open AccessIdentifying Parkinson’s disease subtypes with motor and non-motor symptoms via model-based multi-partition clustering
Identification of Parkinson’s disease subtypes may help understand underlying disease mechanisms and provide personalized management. Although clustering methods have been previously used for subty**, they h...
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Article
Open AccessResource Utilization of Patients with Parkinson’s Disease in the Late Stages of the Disease in Germany: Data from the CLaSP Study
The Care of Late-Stage Parkinsonism (CLaSP) study aimed to collect qualitative and standardized patient data in six European countries (France, Germany, Netherlands, Portugal, UK, Sweden) to enable a detailed ...
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Article
Open AccessAuthor Correction: Report from a multidisciplinary meeting on anxiety as a non-motor manifestation of Parkinson’s disease
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessReport from a multidisciplinary meeting on anxiety as a non-motor manifestation of Parkinson’s disease
Anxiety is a severe problem for at least one-third of people living with Parkinson’s disease (PD). Anxiety appears to have a greater adverse impact on quality of life than motor impairment. Despite its high pr...
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Article
Neuropsychiatric aspects of Parkinson’s disease
Throughout the natural history of Parkinson’s Disease (PD), from the pre-diagnostic phase to end stage disease, neuropsychiatric manifestations represent a core feature of the disease. This review summarises c...
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Article
Dyskinesia in multiple system atrophy and progressive supranuclear palsy
In the differential diagnosis of Parkinson syndromes, the response to l-Dopa is an essential criterion for the diagnosis of idiopathic Parkinson’s syndrome (IPS), and the presence of l-Dopa-induced dyskinesia (LI...
