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Article
Publisher Correction: The metabolite BH4 controls T cell proliferation in autoimmunity and cancer
An Amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
The metabolite BH4 controls T cell proliferation in autoimmunity and cancer
Genetic regulators and environmental stimuli modulate T cell activation in autoimmunity and cancer. The enzyme co-factor tetrahydrobiopterin (BH4) is involved in the production of monoamine neurotransmitters, ...
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Article
Open AccessImpact of mitochondrial nitrite reductase on hemodynamics and myocardial contractility
Inorganic nitrite (NO2 −) can be reduced back to nitric oxide (NO) by several heme proteins called nitrite reductases (NR) which affect both the vascular tonus and hemodynamics. The object...
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Open AccessHepatic Deletion of Janus Kinase 2 Counteracts Oxidative Stress in Mice
Genetic deletion of the tyrosine kinase JAK2 or the downstream transcription factor STAT5 in liver impairs growth hormone (GH) signalling and thereby promotes fatty liver disease. Hepatic STAT5 deficiency acce...