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within Andreas Heger Remove this filter Cancer Research Remove this filter

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  1. Article

    Open Access

    Identification of a candidate prognostic gene signature by transcriptome analysis of matched pre- and post-treatment prostatic biopsies from patients with advanced prostate cancer

    Although chemotherapy for prostate cancer (PCa) can improve patient survival, some tumours are chemo-resistant. Tumour molecular profiles may help identify the mechanisms of drug action and identify potential ...

    Prabhakar Rajan, Jacqueline Stockley, Ian M Sudbery, Janis T Fleming… in BMC Cancer (2014)

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  2. No Access

    Article

    Sequencing depth and coverage: key considerations in genomic analyses

  3. The average depth of sequencing coverage can be defined theoretically as LN/G, where L is the read length, N is the number of reads and G is the haploid genome...

    4. David Sims, Ian Sudbery, Nicholas E. Ilott, Andreas Heger… in Nature Reviews Genetics (2014)