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Article
Prognostic value of scalp EEG ictal patterns in epilepsy surgery of hippocampal sclerosis
Temporal lobe epilepsy associated with hippocampal sclerosis (TLE-HS) is a surgically treatable epileptic syndrome. While the core of pre-surgical evaluations rely on video-EEG, recent studies question the nec...
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Article
Open AccessProfile of sleep disturbances in patients with recurrent depressive disorder or bipolar affective disorder in a tertiary sleep disorders service
Bidirectional relationship between sleep disturbances and affective disorders is increasingly recognised, but its underlying mechanisms are far from clear, and there is a scarcity of studies that report on sle...
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Article
Open AccessClinical characteristics of a large cohort of patients with narcolepsy candidate for pitolisant: a cross-sectional study from the Italian PASS Wakix® Cohort
Narcolepsy is a chronic and rare hypersomnia of central origin characterized by excessive daytime sleepiness and a complex array of symptoms as well as by several medical comorbidities. With growing pharmacolo...
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Article
Subjective sleep disorders and daytime sleepiness in patients with restrictive type anorexia nervosa and effects on quality of life: a case–control study
To evaluate sleep disorders and daytime drowsiness in a cohort of patients affected by anorexia nervosa and their impact on health-related quality of life. We evaluated patients affected by restricting-type of...
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Article
Open AccessLevetiracetam, lamotrigine and carbamazepine: which monotherapy during pregnancy?
Epilepsy treatment during pregnancy is still challenging. The study is aimed at comparing the efficacy and safety of carbamazepine (CBZ), lamotrigine (LTG) and levetiracetam (LEV) monotherapies during pregnanc...
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Article
Excessive daytime sleepiness and fatigue in neurological disorders
Excessive daytime sleepiness (EDS) and fatigue are some of the most frequent symptoms in neurological diseases and could impact on quality of life by increasing the risk of accidents and generally affecting da...
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Article
Feasibility of automated detection of sleep apnea using implantable pacemakers and defibrillators: a comparison with simultaneous polysomnography recording
Sleep-related breathing disorders (SRBD) have been associated with adverse cardiovascular events and prognosis. Some modern pacemakers (PMK) and implantable cardioverter defibrillators (ICD) are equipped with ...
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Article
Sleep Complaints, Sleep and Breathing Disorders in Myotonic Dystrophy Type 2
To update the current knowledge concerning sleep complaints and breathing disorders in myotonic dystrophy type 2 (DM2) and to better understand if sleep and breathing symptoms may add a further clinical defini...
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Article
Comparative Sleep Disturbances in Myotonic Dystrophy Types 1 and 2
To update current knowledge regarding sleep disturbances and myotonic dystrophies so as to better understand if sleep symptoms may help in the early recognition of the two genetic subtypes: myotonic dystrophy ...
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Chapter
Cardiac Autonomic Changes in Epilepsy
The term “Epilepsy” encompasses a broad spectrum of medical and social disorders that affect about 65 million people worldwide and is commonly defined as a tendency to suffer recurrent seizures. In patients wi...
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Article
Beta-amyloid and phosphorylated tau metabolism changes in narcolepsy over time
The aim od this study is to test whether metabolism of beta-amyloid and tau proteins changes in narcolepsy along with the disease course.
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Article
Epilepsy surgery in adult-onset Rasmussen’s encephalitis: case series and review of the literature
Rasmussen’s encephalitis (RE) is a rare immune-mediated condition characterized by drug-resistant focal epilepsy, progressive neurological, and cognitive deficits associated to unilateral hemispheric atrophy. ...
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Article
Sleep disorders in spinal and bulbar muscular atrophy (Kennedy’s disease): a controlled polysomnographic and self-reported questionnaires study
No data are available regarding the occurrence of sleep disorders in spinal and bulbar muscular atrophy (SBMA). We investigated the sleep-wake cycle in SBMA patients compared with healthy subjects. Nine SBMA o...
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Article
Topiramate-induced restless legs syndrome